The drug "Ketonal" (cream) - pain in the joints and tissues recedes

The drug "Ketonal" (cream) is a white homogeneous mass and is intended exclusively for external use. The main active ingredient in the cream is ketoprofen, and additional ones are white petrolatum, sorbitan, fatty acid ester, methylhydroxybenzoate, propylene glycol, isopropyl myristate, magnesium sulfate, propylhydroxybenzoate, polyethylene glycol-45dodecylglycol and purified water.

The drug "Ketonal" (cream) is prescribed as a remedy for external use in the event of muscle or joint pain. The effect of this cream is due to the fact that there is an inhibition of the synthesis of leukotrienes and prostaglandins, which inhibits the activity of the enzyme cyclooxygenase and, to some extent, lipoxygenase.

The medicine "Ketonal" (cream) is very helpful in the presence of arthritis and extra-articular rheumatism and can be used as a monopoly medicine or as part of complex therapy. The drug significantly weakens the pain syndrome that occurs with sports injuries of the joints and soft tissues. The drug does not penetrate into the systemic bloodstream, so there are practically no systemic effects. The medicine excretes along with the urine in the presence of insignificant renal insufficiency, the age and cirrhosis of the liver do not affect the excretion of this agent.

Ketonal (cream) - instructions for use

The use of this cream is effective in the presence of diseases such as extra-articular rheumatism, arthritis, pain syndrome, inflammation of the joints and soft tissues, post-traumatic pains.

Apply the drug "Ketonal" (cream) on the affected area of the skin by careful rubbing, enough twice during the day. The amount of the drug will depend on the size of the lesion. After applying the cream, no tightening bandages should be applied.

Side effects

After the application of this drug, the appearance of such negative consequences as reddening and itching of the skin, urticaria, anomalous photosensitivity reaction, anaphylactic shock, dermatitis, erythema multiforme, Stevens-Johnson syndrome, skin necrosis, purpura. The cardiovascular system can react with the appearance of puffiness.

Contraindications for use

It is impossible to apply Ketonal cream with increased individual sensitivity to ketoprofen, salicylates and other NSAIDs, as well as erosive and ulcerative gastrointestinal lesions, which are in the acute stage, severe liver and kidney diseases, with a tendency to bleeding, during breastfeeding, and Also up to the age of 15 years.

It is not recommended to apply the cream to open wounds that are formed due to eczema, dermatosis or mechanical damage to the skin.

Cases of overdose

Serious cases of an overdose of cream "Ketonal" is not registered. It's just not possible for the drug to get on the mucous membranes. Especially in the eyes. In the event that the skin remains traces of the use of the cream, treatment with its use should be discontinued.

During the treatment with this cream and for two weeks after its cessation it is necessary to be protected from sunlight on affected areas.

In the last trimester of pregnancy, the use of the cream is contraindicated, since it can delay delivery and lead to the onset of pulmonary hypertension in the child, and in the rest of the period it should be used cautiously and only under the supervision of an experienced specialist.

At present, there is no information on the effect of Ketonal cream on psychophysical function.

Although the drug penetrates very poorly through the skin, it can not be taken together with medications that contain methotrexate, since in this case the rate of excretion of methotrexate is significantly reduced and its toxic effect is enhanced.