The drug "Ftalazol": instruction

The drug "Phthalazol" recommends the use for the treatment of acute dysentery (amoeba), colitis, enterocolitis, gastroenteritis, paratyphoid infections, for the prevention of purulent complications after operations on the intestine. The main form of release of the drug are tablets, which are packaged in a contour cell box.

The drug "Ftalazol". Instruction: composition, pharmacokinetics, pharmacodynamics

The active substance of the tablets is phthalylsulfatiazole (phthalazole). The auxiliary components include povidone, potato starch, anhydrous anhydrous colloidal, calcium stearate, talc, magnesium stearate.

The drug is relatively slowly absorbed in the stomach, the intestines, where more of its amount is delayed. Here it also decomposes to sulfatiazole, which has a sufficiently high antimicrobial effect. The effectiveness of the drug is due to the creation of large quantities of this substance in the small intestine, which is very slowly absorbed and eliminated.

The drug is active against almost all Gram-negative, Gram-positive microorganisms. The active substance (phthalylsulfatiazole) exhibits bacteriostatic action.

The drug "Ftalazol". Instruction: method of application, dosage

In acute forms of dysentery, six grams of the drug per day is prescribed. In the future, the dosage and number of doses gradually fall. The duration of therapy is thirty days. For other forms of infections per day, two grams of the drug are recommended. It is necessary to take the drug every six hours. In the next two days, the dose is reduced by half.

The drug "Ftalazol". Instruction: side effects, contraindications

Among the side effects is the appearance of fever, rash, signs of insufficiency of B vitamins, which is observed due to the oppression of the intestinal microflora. In more severe cases, aplastic anemia develops , agranulocytosis.

Contraindications to the use of the drug are hypersensitivity to its components, the presence of Graves' disease, blood diseases, acute hepatitis, age (up to 3 years).

The drug "Ftalazol". Instruction: special instructions

In some cases, it is advisable to use this medication in combination with antibiotics (sulfonamides), which have good absorption properties. With caution, the drug is prescribed to patients who are diagnosed with nephritis or nephrosis.

The drug "Ftalazol" during pregnancy is used in extreme cases. It is able to penetrate the fetus through the placenta, causing unwanted toxic effects.

The drug "Ftalazol" when using lactation is also not recommended, because it is absorbed into breast milk and harm the health of the child.

The drug does not affect the skills of managing dangerous mechanisms, vehicles.

It is necessary to pay attention to possible interactions when using drugs of other pharmacological groups. The drug is incompatible with paraaminosalicylic acid (increased toxicity), oxallicin (decrease in its activity), nitrofuran (increases the risk of development of methaemoglobinaemia, anemia), calcium chloride (decreased function of blood coagulability).

If an overdose occurs, the drug should be discarded and the stomach washed with a 2% solution of sodium hydrogencarbonate or with a suspension of activated carbon. In this case, it is also recommended to use a lot of liquid with increased alkalinity.