Syrup 'Lazolvan'

The drug "Lazolvan", as a rule, is available in the form of tablets and syrup. In this article, we are talking about the liquid form of the drug.

Syrup "Lazolvan" contains the main substance - ambroxol hydrochloride, there are also auxiliary substances: sorbitol, hydroxyethyl cellulose, benzoic acid, glycerol, tartaric acid, raspberry flavor, and purified water. As a matter of fact it is almost transparent liquid, not having color, a little viscous, with a fragrant fruity smell.

Syrup "Lazolvan" has the following pharmacological action: it has secretory, secretory and the main expectorant effect. The drug stimulates serous cells of the human bronchial mucosa, significantly increases the release of a substance such as surfactant in the bronchi and alveoli. Corrects the ratio of serous and mucous components of sputum, broken for various reasons. In addition, the drug activates enzymes hydrolyzing and enhances the liberation of lysosomes from cells. Sputum after application of the drug loses its viscosity. The effect of syrup can also be attributed to an increase in the motor activity of the cilia in the ciliated epithelium and the mucociliary transport of sputum is significantly increased. All of the above actions occur approximately half an hour after taking the medicine, and its active effect lasts for almost 12 hours.

Syrup "Lazolvan" has high absorption values, with a maximum concentration of two hours. It has the property of penetrating the blood-brain and placental barrier and excreted in breast milk. As for the metabolism, dibromantranilic acid and glucuronic conjugates are formed in the liver. From the body is withdrawn half an hour and a half, prolonged forms through 12. The elimination process occurs through the kidneys - about 90% in the form of metabolites of water-soluble, and 5% in unchanged form. If there is a violation of the liver, these processes do not change, but with renal failure may increase the half-life.

Children's syrup "Lazolvan" and adult is indicated for chronic and acute diseases of the respiratory system, during which a certain amount of viscous sputum is released. It can be chronic or acute bronchitis, obstructive pulmonary disease, pneumonia, bronchial asthma with simultaneous difficulty in sputum release, and bronchiectasis.

There are some contraindications to the use of the drug: increased sensitivity to ambroxol or other components of this drug. Contraindicated in the first trimester of pregnancy, with acute need for the second and third trimester can be taken, but with great care and under the strict supervision of the lead doctor. In the process of clinical trials, there were no serious consequences during pregnancy, however, when admission is strongly recommended to follow the rules established by the doctor. When breastfeeding the drug penetrates into the mother's milk, but does not have a negative effect on the baby. Caution is also recommended during lactation and with kidney failure.

Syrup "Lazolvan" is taken by adults for 10 ml or two teaspoons three times a day; Children from 6 to 12 years, one teaspoon, also three times a day; From 2 to 6 - half teaspoon three times; Children under the age of two, should give a syrup on the floor of a teaspoon, but only twice a day. It is recommended to take in the process of eating and drink with liquid.

Syrup "Lazolvan" reviews in its mass has a positive, but there are some side effects: mostly different allergic reactions. With prolonged admission, nausea, vomiting, gastralgia and heartburn may occur.