Reviews, analogues and instructions "Kombigrippa"

Surely, most of the flu patients or ARVI used tablets or Kombigripp powder. The instruction for the use of this remedy indicates that it is particularly effective in combating the symptoms of these diseases (headache, fever, coughing, sneezing, swelling of the nasal mucosa and pharynx, etc.). And how exactly this drug works on the patient's body, what are its benefits and side effects, will be discussed in detail in the article.

Substances included in the drug Kombigripp

The instruction, attached to the "Kombigripp" preparation, indicates that it includes:

• paracetamol,
• Anhydrous caffeine,
• Phenylephrine hydrochloride,
• Maleate of chlorpheniramine.

This selection is not accidental, as they all perfectly complement each other in the process of eliminating the symptoms of influenza and ARVI: caffeine stimulates the nervous system, paracetamol lowers the temperature and relieves headache, and phenylephrine hydrochloride reduces the swelling of the mucous tissues of the nasopharynx and facilitates breathing. Chlorpheniramine maleate reduces tearing, reduces mucus discharge from the nose and relieves the patient from irritation in the nose and throat causing sneezing or coughing.

A similar composition is also available for Lemsil Max Limon, Aidrink, Maxikold and Vix Active Simtomax powders, and Adjikold and Glicoldin tablets.

How does paracetamol, part of the drug "Kombigripp"

Since paracetamol is the main active substance of the drug "Kombigripp" (the instruction to it is offered to your attention), we will talk about it separately.

Paracetamol is a non-narcotic analgesic. Its effect on the human body is manifested in the inhibition of the formation of biologically active substances - prostaglandins. They excitably act on the center of human thermoregulation, located in the hypothalamus (the brain department responsible for the regulation of the operation of many systems). As soon as their amount decreases, this leads to a decrease in the elevated body temperature in the patient.

The anesthetic effect of paracetamol is achieved by the fact that a reduced amount of prostaglandins, of course, to a lesser degree, stimulates the reaction of nerve cells to chemical or mechanical stimuli, as a result of which the pain goes away.

Features of the action of paracetamol on the body of children and adults

Attached to the drug "Kombigripp" instruction draws our attention to the fact that the said drug is transferred in different ways, depending on the age.

As research has shown, paracetamol is more pronounced for children's body, which is part of the drug, while it has fewer side effects than for adult patients. This phenomenon is due to the fact that the disintegration of the named substance in the body of children under 12 years due to the immaturity of many enzymes occurs without the formation of toxic exchange products. In adults, the same is observed and, as a consequence, has a negative effect on the liver of the patient.

What is the difference between the "Combigripp Dexa" preparation: the instruction

Many doctors offer their patients to get rid of the manifestations of the flu or ARVI use tablets "Kombiggrip Dex". This drug, in addition to the properties listed above, characteristic of the "Combigripp" tablets, also has a pronounced antitussive effect. It is achieved due to another component of the drug - destrometorfan hydrobromide.

This substance is able to act directly on the cough center, so that the patient's unproductive, exhausting cough becomes more rare and less pronounced.

By the way, similar composition is also available in tablets "Gripex Active Max", "Helpex Anticold Dx", as well as in capsules or "Combinex" syrup.

Approximate dosage of the drug

Naturally, no matter how detailed the instructions attached to the drug, "Kombigripp", like other medicines, should be prescribed by a doctor. Only by following the recommendations of a specialist who accurately determines the severity of the patient's condition, he will be able to get rid of his illness in a short time, without getting complications, which are especially dangerous for the flu.

Most often, this drug is prescribed for adults and children after 12 years in a dose not exceeding two tablets in one session. And this is done up to four times a day.

Children aged 6-12 years are offered to drink half or a whole tablet up to four times a day. By the way, the interval between receptions should be no less than four hours. And take medicine only after eating, after half an hour.

The duration of treatment, as a rule, is not more than a week. And alcohol at this time should always be excluded.

Who is contraindicated with the drug Kombigripp (tablets)

Instructions for use of the described drug draws the attention of consumers to the fact that some people its use may be dangerous. These include patients:

• With prostatic hypertrophy;
• With severe forms of atherosclerosis;
• Hypertension;
• With acute pancreatitis and hepatitis;
• Thrombosis of peripheral arteries;
• Severe forms of ischemia of the heart;
• Violations of cardiac patency
• And ventricular tachycardia.

As the instructions to the Kombigripp medication emphasize, the pills are not prescribed to people who are sick with alcoholism, pregnant women and children under the age of six.

Patients taking drugs related to MAO inhibitors, the said agent is also contraindicated.

How is drug overdose manifested?

Signs of an overdose both with the drug "Kombigripp", and with the "Combigripp Dex" means the instruction connects with the substances that make up their composition. As a rule, they often appear as symptoms of paracetamol overdose. Signs of this condition at first are nausea, vomiting, increasing general weakness and the appearance of pain in the right hypochondrium.

After a day, the symptoms of hepatic pathology most often become apparent in the patient. They are manifested in the form of edema, increased abdominal pain, fever and jaundice. If during this period the patient was not provided with timely assistance, then 72 hours later he may develop necrosis (death) of the liver. This is accompanied by the appearance of bleeding and the progression of hepatic encephalopathy, leading the patient to a coma.

In a situation where an overdose is found (regardless of whether the pills have been applied or "Combi Gripp" powder), the instruction recommends that you wash the patient's stomach and seek qualified help in a medical institution. To neutralize the effect of paracetamol , N-acetylcysteine or methionine is used. In addition, measures are being taken to maintain the cardiovascular system and normalize the water-electrolyte balance.

Composition of the ointment "Kombigripp"

In addition to the tablets or powder described above, another form of the drug "Kombigripp" - ointment is produced. The instruction for this medication indicates in its composition the following active substances:

• menthol,
• camphor,
• thymol,
• Methylsalicylate,
• Eucalyptus oil,
• turps.

Ointment is used externally for diseases affecting the upper respiratory tract, as well as for muscle and joint pain. The effect is achieved due to the local irritant effect of the constituent elements of the ointment, which stimulate the release of substances involved in regulating vascular permeability and affecting the severity of pain.

When the ointment is applied to the skin, the patient experiences a feeling of cold, which translates into a slight burning and tingling sensation. She is prescribed to children of two years and adults and is administered three times a day for a week.

Ointment is contraindicated in pregnant women, since its components (camphor and eucalyptus oil) can easily penetrate the skin and placental barrier. Patients prone to convulsions or patients with epilepsy also do not prescribe this drug, since sharp smells can trigger the onset of an attack.

How and in what cases is applied ointment "Kombigripp"

If the patient is ill with tracheitis, pharyngitis, laryngitis or rhinitis, the doctor can appoint "Combigripp" (ointment) as part of a complex treatment. Instructions for use of this tool indicate that it can be effective in the treatment of arthralgia or myalgia.

When a respiratory disease occurs, a sufficient amount of ointment (up to 4 g) is applied to the skin in the region of the chest (closer to the throat). It is gently rubbed, then cover this area with a dry warm cloth. By the way, it should adhere to the body loosely, so that the active substances evaporating from the drug can reach the nose and throat of the patient.

In the case where the ointment is used for muscle or joint pain, the applied volume should also be sufficiently large. They rub the affected area and leave it open.

Features of use of ointment "Kombigripp"

During the application of the "Kombigripp" ointment, certain rules must be observed.

• Protect the mucous membranes from getting the ointment.
• Avoid application of the product to damaged skin.
• If irritation occurs as a result of the application of the ointment, you must urgently stop using it and consult a doctor.
• Ointment is not used to lubricate the inner surfaces of the nose.
• The drug is not worn on large areas of the skin.
• It is not used in cases when cough is caused by smoking, asthma, emphysema, etc., and also if it is accompanied by intensive separation of sputum.
• In cases where, as a result of treatment with the "Combigripp" ointment, cough does not disappear for a week and is accompanied by fever, a rash or a persistent headache, you should consult your doctor to review the treatment tactics.