Preparation "Istenon": reviews. Instenon: instructions for use and analogues

What is a tool like "Instenon"? The instructions for use, the price and the properties of this medication will be described later.

Composition, form, description of the medicine

In what form is the above-mentioned drug sold? What does consumers say about this? "Instenon" is produced in the following forms:

• Tablets are round with a shiny and flat surface, covered with a white membrane. The main substances in their composition are: hexabendine (in the form of hexabendine dihydrochloride), as well as ethophylline and etamivan. In addition, the composition of this drug includes additional elements: talc, magnesium stearate, pregelatinized starch, corn starch and lactose monohydrate.
• Transparent and colorless solution "Instenon" (injections), intended for intramuscular or intravenous administration. Its active ingredients are also hexabendine (in the form of hexabendine dihydrochloride), ethophylline and etamivan. As for the auxiliary substances, disodium edetate, water d / and propylene glycol are used as such.

Pharmacology

How does the agent work? What does the doctor say about this? "Instenon" is a combined medicine that improves metabolism, as well as blood circulation of the brain.

The effectiveness of this drug is due to the properties of its basic substances. Let us consider them in more detail.

Thanks to activation of the reticular formation, etamivan is able to normalize the work of neural subcortical-stem structures and cortical complexes.

Hexadendin improves, and also speeds up the process of utilization of glucose and O2 by activating pentose cycles and anaerobic glycolysis. This occurs only in conditions of oxygen starvation and ischemia, when oxidative aerobic phosphorylation is significantly impaired. Stimulation of anaerobic oxidation is carried out by the energy substrate for the purpose of metabolism and synthesis of mediators, as well as the restoration of synaptic transmissions.

It should also be said that hexobenzene is able to stabilize the mechanisms (physiological) of autoregulation of the blood flow (cardiac and cerebral), which has a direct connection with the action of pyruvate and lactate (i.e., products of anaerobic glycolysis) on the receptor apparatus of capillaries and intracranial arterioles.

What role does etofillin play in the drug "Instenon"? The instruction, the reviews report that this substance activates the myocardial metabolism and increases the minute volume of the heart, which further contributes to the increase of pressure (perfusion) in the ischemic vessels. In this case, systemic blood pressure does not change at all.

The stimulating effect of this phyllin on the NS is also manifested by stimulation of the midbrain and other subcortical formations, as well as stem nuclei and centers (including the nuclei of CMN, the center of autonomic regulation, the vasomotor and respiratory centers and the vagus nerve).

When using the drug "Instenon", the analogues of which are listed below, in cases of trauma of the skull and brain (closed), ischemic stroke, neurological disorders are eliminated, the patient's consciousness restored and the vegetative system activated.

Indications

At what conditions is the drug most effective? What does this say about the reviews? "Instenon" is indicated for use when:

• Post-stroke states;
• Diseases of the brain of vascular origin, as well as associated with age-related changes in the patient;
• Insufficiency of the blood supply to the brain and its consequences;
• Dizziness, which were caused by disorders (functional) of the brain.

Prohibitions to use

The drug "Instenon" (injections and oral forms of the drug have the same contraindications) is prohibited to be prescribed for:

• Convulsive syndrome;
• A state of strong excitation;
• Symptoms of high blood pressure (intracranial), including prolonged headache, vomiting and visual impairment;
• Epilepsy;
• Hemorrhages in the brain;
• Hypersensitivity to the ingredients of the drug.

With caution, the drug should be used after a stroke, as well as with stenosis of the artery (carotid), arisen due to arteriosclerosis.

Preparation "Instenon": instructions for use

The price of this medication is about 350-400 rubles. How should it be used? Depending on the severity and type of disease, the agent in the form of a solution is administered intramuscularly or slowly intravenously. To do this, use 1 ampoule of the drug 2 times a day.

Also, the medication can be prescribed in the form of a dropwise intravenous infusion. In this case, it is also prescribed for 1 ampoule 2 times a day together with 250 ml of a 5% solution of levulose.

After improving the patient's condition, therapy can be continued with the oral form of the drug. In this case, the tablets are taken orally in an amount of 1-2 pieces three times a day. The maximum daily dosage of this drug is 5 tablets. This therapy is carried out for six weeks.

Side effects

According to experts, the drug "Instenon" rarely causes negative reactions. In some cases, when used in high dosages, the patient may have a headache, as well as decrease blood pressure and develop hyperemia on the skin of the face.

Overdose and Interaction

Signs of an overdose of this drug are headaches, facial hyperemia and tachycardia. To eliminate such conditions, you must cancel the drug, and then resume its use, but at a lower dosage.

With the parallel use of the drug "Instenon" and the means that reduce the activity of platelets (including acid acetylsalicylic), it is possible to increase the antiaggregant effect, which is due to the influence of hexiodine.

When taking caffeine in large doses, it is possible to decrease the therapeutic effectiveness of Instenon.

Special Information

What should patients know before taking this medication? According to the attached instructions, sometimes with rapid intravenous injection of "Instenon" in the patient significantly lowered blood pressure. In this regard, the duration of infusion of the first dose should not be less than three minutes.

During treatment with this remedy, the patient must be extremely careful when working with dangerous mechanisms and driving a car.

Similar medications and reviews

"Instenon" can be replaced by such means as "Cytoflavin", "Armadin", "Glycine", "Boluses of Huato", "Keltikan", "Mexidol", "Cortexin", "Mexiprem", "Nucleo CMF Forte", "Neurotropin "," Tryptophan ". It should be noted that these drugs have their own indications and features, so they should be appointed only by an experienced specialist.

What do consumers say about the drug in question? According to their allegations, this medication rarely contributes to the development of any complications, so it is prescribed even to children. His reception significantly improves cerebral circulation, as well as eliminates other problems with blood vessels.

The only drawback of this drug is the rapid adaptation of the body to the drug. In this regard, we can safely say that "Instenon" is a course aid that is not intended for continuous use.