"Lizinopril" - from what these tablets? Instructions for use, analogues, reviews

The most common disease in the adult population is hypertension. The causes of hypertension are very diverse. At such times a person feels headaches, a feeling of fatigue, maybe nausea or vomiting. Fighting such a state is vitally important. After all, the consequences of high blood pressure are a stroke, a heart attack. Therefore, along with the elimination of causes, it is necessary to use drugs that lower blood pressure. One of these drugs is Lizinopril. What are these tablets from? How they are used, how they work, and also what are the analogues of this drug, we will consider further.

In what form is Lizinopril produced?

In what form is Lizinopril produced? The form of release - a tablet. They are flat shapes, Round, with a risk on one side. Depending on how much the active substance of lisinopril dihydrate is contained, the tablets have a different color:

1. Dark orange color - active substance 2.5 mg.
2. Orange color - 5 mg.
3. Pink color - 10 mg.
4. White color - 20 mg.

The auxiliary components are as follows:

• Lactose monohydrate;
• corn starch;
• Methylene chloride;
• Povidone;
• Magnesium stearate;
• dye.

How does "lisinopril" work on the body?

The drug "Lizinopril" has the following effects:

1. Lowers blood pressure.
2. Is able to narrow the vessels.
3. Prevents heart remodeling processes.
4. Prevents the development of ischemia.
5. Increases the excretion of sodium ions from the body.

The active substance of lisinopril dihydrate inhibits the process of angiotensin-1 transition into angiotensin 2, which helps to reduce the formation of the aldosterone hormone. The process of biosynthesis of prostaglandins is also stimulated.

The drug starts to work after 1 hour. After 6-7 hours the drug is maximized. With the regular administration of the drug "Lizinopril" the curative effect will be visible after a few days. A persistent positive effect will be achieved if taken at least two months.

To the preparation "Lisinopril" (tablets), the instruction for use indicates that not more than 60% of the drug substance is absorbed in the digestive tract. Biological availability of the active substance is 25%. Half-life is an average of 12 hours.

Who is prescribed lisinopril?

Tablets "Lizinopril" indications for use are as follows:

1. High blood pressure.
2. Problems in the work of the heart.
3. Early stage of myocardial infarction.
4. Diabetic nephropathy.

Tablets from the pressure of "Lizinopril" are more effective in combining therapy and preventive measures. In combination with antihypertensive agents, it is possible to achieve good and stable results

We found out the composition of the drug "Lizinopril", from which these pills and to whom they are prescribed. Of course, the drug of this action has contraindications to the use.

Who should not use lisinopril?

Who should not take Lysinopril (pills)? Instructions for use indicate the following diagnosed diseases:

1. Special sensitivity, intolerance of the constituents of the drug.
2. Lactose intolerance.
3. Angioedema or idiopathic edema.
4. Intolerance to ACE inhibitors.

Also, you can not use the drug "Lizinopril" to patients who are less than 18 years old.

Especially cautiously the tablets from the pressure of increased "lisinopril" should be taken:

• To old people;
• Patients with diabetes mellitus;
• With IHD;
• In the presence of systemic diseases;
• If there are kidney diseases;
• With insufficient cerebral circulation;
• In the presence of heart failure in a chronic form.

How to take Lizinopril tablets?

Take lisinopril once a day. It is recommended to do this at the beginning of the day. Drink plenty of fluids.

If you take Lizinopril tablets (indications for use are described above), the recommended scheme is as follows:

1. For the treatment of diabetic nephropathy, the initial dosage should be the minimum of those that have "lisinopril" (tablets). 10 mg per day - the best option. Further it is possible to increase the dose to 20 mg.
2. In the case of essential hypertension, the initial dose is 10 mg. For maintenance therapy, 20 mg, and the maximum is 40 mg. It should be borne in mind that a stable effect will be observed after 1-2 months. If the patient takes diuretics, they should be canceled 2-3 days before the start of the course with Lisinopril.
3. When chronic heart failure is used, "Lizinopril" tablets. The application starts with a dose of 2.5 mg and gradually increases for 3-5 days to a maintenance dose of 5-10 mg per day. In this case, the dosage of the diuretic should be reduced.
4. Renovascular hypertension is treated with an initial dose of 2.5-5 mg per day. At the same time, it is necessary to keep blood pressure, kidney function under control. Given these indicators, it is necessary to choose a maintenance dose of the drug.

Possible side effects

In any case, it is necessary to take carefully tablets "Lizinopril". The instruction indicates the appearance of possible side effects:

• Headaches, dizziness;
• Nausea, diarrhea;
• fast fatiguability;
• dry cough.

Very rarely there are such side effects of the drug:

1. Drowsiness, confusion.
2. Pain in the chest, shortness of breath, bronchospasm.
3. Bradycardia.
4. Sudden decrease in blood pressure.
5. Increased sweating.
6. Pain in the muscles, tremors, cramps.
7. Excessive hair loss.
8. Hypersensitivity to ultraviolet radiation.
9. Allergic reactions.
10. Change in blood counts.

Before using the drug, consult a doctor. He will choose the right dosage. This will help reduce the risks of side effects.

Use of "Lizinopril" for children and pregnant women

Tablets from the pressure of "Lizinopril" are not used to treat children and adolescents who are under 18 years of age. Because their influence on the children's body is not fully understood.

Pregnant women are not prescribed lisinopril during lactation. Since the drug may affect the development of the fetus, death is possible. During the lactation it is assumed that the drug can penetrate into breast milk.

Lizinopril and alcohol

It should be noted that if you take Lysinopril, you should completely eliminate the use of drinks that contain ethyl alcohol. "Lizinopril" increases the toxic effect of alcohol.

Special instructions for the use of Lysinopril

There are some peculiarities when taking Lizinopril.

When carrying out therapy, it is necessary to regularly monitor the functioning of the kidneys. It is necessary to compensate for the loss of fluid and salts before taking the drug.

Excessive loss of moisture after taking diuretics, salt-free diet or vomiting can lead to the development of arterial hypotension. Particular attention should be given to patients who have impaired renal function, and there is stenosis of the renal artery, severe congestive heart failure.

You can not take "Lizinopril" with cardiogenic shock and acute myocardial infarction.

If treatment with lisinopril causes angioedema, treatment should be discontinued and patient supervision established.

It is necessary to be cautious in the treatment of elderly patients, as very often they are intolerant of "Lizinopril".

When taking the drug is not necessary in hot weather to intensively engage in physical exertion, it can contribute to a sharp drop in blood pressure.

If side effects occur in the form of dizziness, blocking or worsening concentration of attention, then you should abandon the management of transport and work that requires increased attention.

In their own way, the tablets "Lizinopril-ratiofarm" are assimilated. The instruction notes that the active substance is not biotransformed in the liver, so it can be administered to patients with impaired liver function.

How does lisinopril interact with other drugs?

Consider how "Lizinopril" works simultaneously with some drugs:

1. Joint use with oral hypoglycemic and insulin can promote the development of hypoglycemia.
2. With simultaneous use of the drug with lithium carbonate, intoxication of the body with lithium is increased.
3. The therapeutic effect of "Lizinopril" is reduced by joint admission with adrenomimetics and non-steroidal anti-inflammatory drugs.
4. Salicylic acid enhances its neurotoxic effect.
5. Contraceptive medications are becoming less effective.
6. Diuretic potassium-sparing agents together with "lisinopril" can cause the development of hyperkalemia.
7. Simultaneous use of ACE inhibitors and NSAIDs increases the risk of kidney failure.
8. Lizinopril in combination with cardiac glycosides can enhance the side effects of these drugs.

Preparations of gold in combination with "Lizinopril" can lead to the development of facial hyperemia, lowering blood pressure, vomiting and nausea.

Symptoms of an overdose of Lysinopril

If you take the drug "Lizinopril", from what these tablets need to know and observe the recommended dosage.

In case of an overdose, symptoms such as:

• Severe fatigue;
• drowsiness;

• Dry mouth;
• Arterial pressure drops strongly;
• Violation of urination;
• Tachycardia, bradycardia;
• anxiety.

In such cases, symptomatic therapy is used. It is possible to prescribe intravenously saline solution, the use of hemodialysis. When angioedema appears, antihistamines are used. With persistent bradycardia, electrostimulation is performed.

In the case of using the drug "Lizinopril" it is necessary to keep under control the performance of vital organs, as well as the concentration of serum electrolytes and keratin.

Analogues of the drug "Lizinopril"

If you can not find the tablet "Lizinopril" in the pharmacy, the analogs of the drug will help you replace it. These drugs have almost the same composition with the same active substance.

These are such drugs as:

• "Dapril";
• "Equator";
• "Diroton";
• "Lizitar";

• "Diropress";
• "Lizakard";
• Lizinopril Hexl;
• "Lizonorm";
• "Liten".

Before you buy an analogue of the drug, talk to your doctor. And also specify which dosage of the analogue you need to use.

Reviews about the drug "Lizinopril"

Tablets from the pressure "Lizinopril" reviews are very different. Patients are noted that the decrease in blood pressure occurs gradually, without sudden changes. Many are satisfied that they could not pick up the drug for a long time from high blood pressure, and only after the appointment of Lysinopril it came back to normal.

Many patients note the absence of side effects even after a long course of therapy. Arterial pressure remains within normal limits, even if taken once a day.

Lizinopril tablets also receive feedback about side effects. Most often, patients report the appearance of a dry cough, if the drug has to be taken for several months.

There is also a category of patients who did not get the Lysinopril preparation. But these are much fewer than those to whom this medicine helped to feel better.

It should be noted that drugs to lower blood pressure should be taken strictly after consulting a doctor. It is not always possible to find the active drug the first time. But only by the method of selection together with the doctor, keeping your health under control and watching how your body reacts to the new drug, you can find the most effective medicine. It is in this case that you will be able to choose the optimal treatment regimen and a medication that will not harm your body.

If you are prescribed a drug "Lizinopril", from what these pills and how you should take them, should explain only the doctor, and before use, be sure to read the instructions. Self-treatment with increased pressure will not lead to anything good. Follow the recommendations of specialists and be healthy.