"Gentamycin sulfate": instructions for use, analogues and reviews

Many infectious and inflammatory processes in the body can not do without the use of antibiotics. A group of these drugs kills harmful microorganisms and pathogens. One of the known antibacterial drugs is "Gentamycin sulfate". It is considered an antibiotic with a wide range of uses and is used to treat humans and animals.

Form and composition of the preparation

The product is available as a 4% solution for injections and eye drops. The main substance in the drug is gentamycin sulfate in a dose of 4 mg in one milliliter. It belongs to the group of aminoglycosides and is considered to be a wide-spectrum antibiotic.

The drug has an anti-inflammatory and bactericidal effect. Has a high activity against anaerobic gram-negative bacteria and Gram-positive cocci. After intramuscular injection, the drug is rapidly absorbed. The maximum effect is achieved within an hour after the injection. Almost completely does not bind to blood proteins. The antibiotic in the extracellular fluid is distributed to all organs and systems. The drug is not metabolized and mainly excreted by the kidneys, slightly - with bile. Has the property to pass through the barrier of the placenta drug "Gentamycin sulfate". Use, side effects - all this should be studied before planning therapy.

Indications

The drug is prescribed for infectious and inflammatory processes in the body, which are caused by antibiotic-sensitive microorganisms. For parenteral administration :

• cystitis;
• Acute cholecystitis;
• Suppurative lesions of the skin;
• Burns of different degree;
• Pyelonephritis;
• cystitis;
• Diseases of joints and bones of an infectious nature;
• sepsis;
• peritonitis;
• Pneumonia.

When used externally:

• furunculosis;
• Folliculitis;
• seborrheic dermatitis;
• Infected burns;
• Wound surfaces of different etiology;
• sycosis.

For local application:

• Blepharitis;
• Blepharoconjunctivitis;
• Dacryocystitis;
• Conjunctivitis;
• Keratitis.

With such pathologies, "Gentamycin sulfate" is used. Instructions for use are in the middle of the drug store with the medicine.

Contraindications:

• Hypersensitivity to antibiotics;
• Severe kidney and liver pathology;
• Disturbance of the auditory nerve;
• Fruit bearing;
• breast-feeding.

Also, the antibiotic Gentamycin Sulfate is not prescribed in ampoules with uremia.

Dosage

The drug is administered individually for each patient. Dosage depends on the severity of the process and the hypersensitivity to the agent. At a time, 1 to 1.7 mg per kg of body weight is administered. The drug is injected into the vein or intramuscularly. The medicine is used two to four times a day. The maximum dosage per day can not be more than 5 mg. The course of therapy is 1.5 weeks.

Children after two years of the drug is administered several times a day in the amount of 1 mg per kilogram of weight. For children under the age of one month, the daily dosage can not be more than 2-5 mg per kilogram of body weight. Antibiotic is administered several times a day.

For topical administration, eye drops drip 1 drop every two hours. For external use, the substance is prescribed up to three times a day. People with impaired renal function, depending on the clinical picture, are corrected the drug "Gentamycin sulfate". Eye drops are buried directly into the bag of the conjunctiva of the diseased eye.

Interaction with other means

It is not recommended to share with the following drugs:

• "Vancomycin";
• "Cephalosporin";
• "Ectric acid";
• "Indomethacin";
• Means for anesthesia;
• Analgesics;
• Loop diuretics.

Before planning therapy, it is necessary to carefully study the interaction of other drugs and the antibiotic "Gentamycin Sulfate".

Neglect of recommendations may lead to the development of the following side effects:

• nausea;
• Vomiting;
• Increased bilirubin in the blood;
• anemia;
• Thrombocytopenia;
• leukemia;
• migraine;
• dizziness;
• Proteinuria;
• Disorders of the vestibular apparatus.

It can also cause allergic reactions of "Gentamycin sulfate". Drops and solution in rare cases can lead to edema Quincke or anaphylactic shock, which is fraught with serious complications. When using an antibiotic, it is necessary to monitor the functions of the kidneys, auditory and vestibular apparatus.

"Gentamycin sulfate" - antibiotic for animals

Pets can also be prone to bacterial infection. To treat a diseased animal, special groups of antibiotics are used. Such preparations include "Gentamycin sulfate". It belongs to the group of aminoglycosides and is a mixture of gentamycins C1, C2 and Cla. The drug includes gentamicin at a dose of 40 and 50 mg in one milliliter of solution. The product is stored at a temperature of no more than 25 degrees, in a dry and inaccessible place for babies. Two years - the expiration date of the drug "Gentamycin sulfate". Instructions for use for animals will tell in detail about the indications and dosage of the drug.

Act

The drug has a wide range of effects and has activity against gram-positive and gram-negative microorganisms. After the introduction of the drug, it penetrates into all organs and systems in a short time. After one hour, its maximum activity is observed and lasts for 8 hours. It is excreted mainly with urine and in a small concentration with faeces of the animal.

The medicine is prescribed in the treatment of gastric, intestinal, peritonitis, meningitis, pyelonephritis and other diseases in the pet. The drug is administered twice a day at intervals of 10 hours. Orally, Gentamicin Sulfate is administered to animals.

Dosage

To treat horses, the antibiotic is administered intramuscularly at a dose of 2.5 mg per kilogram of body weight. The duration of therapy is from 3 to 5 days. For cattle, the dose is given at a rate of 3 mg per kilogram of body weight for 5 days. Also, the drug can be administered orally at a dosage of 8 mg per kilogram of body weight.

Pigs are injected intramuscularly at a rate of 4 mg per kilogram of body weight. The duration of therapy should not exceed three days. Orally, the drug is used at a dose of 4 mg per kilogram of body weight for 5 days. Dogs and cats are injected intramuscularly with 2.5 mg of solution per kilogram of body weight. Treatment takes up to seven days.

When used internally, the drug is not absorbed in the stomach, but only after 12 hours in the intestine. The intramuscular injection can only vet the antibiotic "Gentamycin sulfate". An animal guide describes methods of administering a medicament.

special instructions

It is forbidden to use an antibiotic with other groups of nephrotic drugs, especially with kidney pathology and hearing impairment. Slaughter of an animal is allowed only three weeks after the last dose of the drug. The remedy does not affect the simplest fungi, viruses and anaerobic bacteria. Only a professional veterinarian can competently calculate the dose of the drug "Gentamycin sulfate 4%" and cure the pet.

The drug "Gentamicin"

The drug refers to antibiotics from the group of aminoglycosides, which are widely used to treat many diseases. The agent has the following effects on the body:

• Bactericidal;
• Anti-inflammatory;
• Has a high activity in relation to Gram-positive and Gram-negative bacteria.

The drug is available in the form of a solution. After intramuscular injection, the drug is rapidly absorbed into the tissues of the whole organism. The greatest bioavailability is observed in half an hour. Half of the drug is excreted in urine after 3 hours. Penetrates through the placenta, therefore it is not recommended to prescribe the drug "Gentamicin" and its analog "Gentamycin sulfate" during pregnancy. Instructions for use of these products contain useful information and a description of antibiotics.

Indications and contraindications

Therapy of infectious and inflammatory diseases, which are caused by microorganisms sensitive to the active ingredient, can be performed using the "Gentamicin" agent. The drug is used for parenteral, external and topical administration.

Contraindications:

• Hypersensitivity to the aminoglycoside group;
• Fruit bearing;
• lactation;
• Severe degree of renal failure;

Before the beginning of the medical process, it is worthwhile to carefully study all the contraindications to the use of antibiotics "Gentamycin" and "Gentamycin Sulfate".

Dosage

The medication is prescribed individually, the dose depends on the severity of the disease. For intramuscular and intravenous administration, the drug is calculated in a dose of 1 to 1.7 mg per kilogram of body weight per time. In a day, the drug is administered two or three times. The maximum daily allowance for an adult should not exceed 5 mg / kg, and for children - 3 mg per kilogram of weight. The medicine is introduced for 7 days. Eye drops are used three times a day and are instilled by one drop directly into the affected eye. Externally, the antibiotic is applied four times a day. In severe renal disease, the drug is prescribed according to the clinical picture, and the dosage can be adjusted. For children, the daily rate depends on the age and condition of the body.

Drug Interactions

The drug "Gentamicin" is not recommended for use in combination with the following drugs:

• "Vancomycin";
• "Cephalosporin";
• "Ectric acid";
• "Indomethacin";
• Analgesics;
• Drugs for anesthesia;
• Diuretics.

They have the same composition and indications for use of the drug "Gentamicin" and a solution of "Gentamycin sulfate 4%". Both agents have an increased bacterial and anti-inflammatory property.

The drug "Gentamicin-Ferein"

The drug refers to the group of aminoglycosides and is widely used for the treatment of many organs and systems. Has increased activity to Gram-positive and Gram-negative anaerobic bacteria. Has a bactericidal effect. After the introduction of intramuscularly and intravenously, the antibiotic is absorbed into all organs and tissues of the body.

40 minutes after the injection, the drug reaches its maximum activity, which lasts for 12 hours. The drug is not metabolized and is excreted in the urine. Has the ability to penetrate the placental barrier.

Indications and contraindications

The drug is used for parenteral, topical and topical use in the treatment of infectious and inflammatory diseases.

Contraindications:

• pregnancy;
• breast-feeding;
• Pathology of the kidneys and liver;
• Hypersensitivity;
• Neuritis of the auditory nerve.

Dosage of the drug "Gentamicin-Ferein"

For adults, the drug is administered in an amount not exceeding 5 mg per kilogram of body weight per day. At one dose, the dose ranges from 1 to 1.7 mg per kilogram of patient weight. The course of treatment depends on the severity of the process and ranges from 7 to 10 days. The drug is found two or three times a day

For children, the dosage is 3 mg per kilogram of body weight per administration. The medicine is injected twice a day. Patients with renal insufficiency, the dosage of the antibiotic is constantly adjusted and depends on the clinical indications.

Eye drops are used every 4 hours and are buried in the affected eye one drop. External remedy is appointed three or four times a day.

Possible side effects:

• nausea;
• Vomiting;
• Increased bilirubin;
• anemia;
• Leukopenia;
• drowsiness;
• migraine;
• Disorders of the vestibular apparatus;
• deafness;
• Allergic reactions, up to Quincke's edema.

Similar side effects can have a solution of "Gentamycin sulfate 4%" during the treatment of infectious and inflammatory processes in the body.

Reviews about preparations based on gentamycin sulfate

Medicines do not belong to the antibiotic of the new generation, but it is quite good and in our time is used to treat microbial diseases. Therefore, the pharmaceutical market is represented by a variety of products, which includes gentamicin. It is not only solutions for injections, but also creams, ointments, eye drops. The medicine affects the genetic information that is embedded in the cells of the causative agent of the disease. The active ingredient is absorbed into the tissues of the body in a short time and begins its antibacterial action.

In most cases, the drug is well tolerated, but can cause an allergic reaction. Also, an antibiotic can be taken from birth. For this, there is a special scheme for calculating the dosage. This antibiotic is widely used in veterinary medicine. It helps the animals get rid of the infection and normalize the work of the stomach and intestines.

Sometimes the medicine "Gentamicin" can lead to deafness, and this is its main drawback. Studying all the reviews, especially doctors, you can understand what a potent antibiotic is this drug. It has a high activity against gram-positive and gram-negative anaerobic organisms. Also in the complex is prescribed for the treatment of pneumonia and meningitis. It is necessary to strictly observe the dosage of the drug in order to avoid side effects. According to many experts, the drug "Gentamycin sulfate" is toxic. Its constant use can affect the performance of all body systems. Antibacterial agents should not be used without consulting a specialist.