Antibiotic Amoxiclav: Description of the preparation

"Amoxiclav" is an antibiotic from a number of penicillins with a beta-lactamase inhibitor.

The drug "Amoxiclav" has a white or yellowish-white color and is intended for the manufacture of a solution for intravenous administration. In the 1fl. The main substance is amoxicillin (1 g or 500 mg in the form of sodium salt) and 200 mg or 100 mg of clavulanic acid as an auxiliary. Produced amoksiklav qwiktab in a cardboard pack of 5 bottles.

Pharmacological properties

Semisynthetic penicillin antibiotic with bactericidal properties and a wide spectrum of action directed at gram-positive and gram-negative bacteria. Antibiotic "Amoxiclav" is active against aerobic bacteria, for example, Nocardia asteroides Streptococcus, spp., Staphylococcus aureus, Corynebacterium spp., Staphylococcus epidermidis, Listeria spp; Gram-negative aerobic bacteria: Bordetella pertussis, Helicobacter pylori, Campylobacter coli, Aeromonas spp., Gardnerella vaginalis, Escherichia coli, Moraxella catarrhalis, Proteus vulgaris, Pasteurella multocida, Morganella spp., Providencia spp. Campylobacter jejuni; Aerobic bacteria: Bacteroides spp., Prevotella melaninogenica, Actinomyces israelii, Clostridium spp., Treponema pallidum, Fusobacterium and others.

Indications

Infectious inflammatory infections caused by microorganisms that are sensitive to this drug: acute and chronic sinusitis, pharyngitis, otitis media, tonsillitis, zaglugal abscess; Pneumonia, bronchitis (acute and chronic); Cholangitis and cholecystitis; Gynecological infections and urinary tract; Gonorrhea and chancroid; Also for the prevention of infectious diseases after surgery, etc.

Contraindications: To antibiotics of the penicillin group , clavulanic acid or to amoxicillin, hypersensitivity; In the anamnesis cholestatic jaundice with violation of the liver functions caused by this drug. Patients with hepatic insufficiency or hypersensitivity to antibiotics of a number of cephalosporins drug is prescribed very carefully. During pregnancy or lactation, the antibiotic "Amoxiclav" should be prescribed exclusively according to the indications.

Doses and route of administration

Enter intravenously for 2-3 minutes. Children who are older than 12 years are prescribed antibiotic "Amoxiclav" in a dose of 1.2 grams per day with a time interval of 8 hours, in severe cases every 6 hours. Beginning at 3 months, The daily dose will be 30 mg / kg of body weight with the same interval. Treatment with this drug lasts 5-14 days (sometimes more)

Side effects

Symptoms: nausea, diarrhea, loss of appetite, vomiting; There are rarely violations of the liver. Very rarely - pseudomembranous colitis, hepatitis and cholestatic jaundice. In the form of an allergic reaction: erythematous rashes, hives, itching; Sometimes angioedema, is also very rare, but occurs with Stevens-Johnson, as well as exfoliative dermatitis. There is a small chance of anaphylactic shock.

An overdose of the drug

Symptoms: diarrhea, persistent vomiting, severe pain in the abdomen; Anxiety, dizziness, insomnia, even convulsions. Special instructions. During the use of the drug, you need to monitor the liver, hematopoiesis and kidneys. In large doses, the use of amoxiclave threatens to increase the level of glucose in the urine. Simultaneous administration with disulfiram should be avoided.

Terms and conditions of storage

Antibiotic "Amoxiclav" must be stored in a place where there is no light and inaccessible to children. The temperature should not exceed 25 ° C. The preparation is only 2 years. The medicine is dispensed only by prescription.

Remember that it is not recommended to take antibiotics without a doctor's prescription , so consult your doctor beforehand. After the course of the drug, there may be an intestinal dysbiosis. To avoid this, if there are no special contraindications, during the period of treatment with "Amoxiclav" it is recommended to take preparations like "Bifidobacterin", etc. A specific agent is chosen by the doctor according to the indications and depending on the concomitant diseases and the situation.

Be healthy!