Thickness of the endometrium. Hyperplastic processes in the uterine mucosa

Obviously, the formation of a normal pregnancy requires the presence of a healthy embryo and a receptive (capable of taking it) of the mucous uterus. It is also obvious that in the middle of the cycle a thin endometrium (less than seven millimeters) causes a sharp decrease in the probability of conception. If less than five millimeters are detected, the possibility of pregnancy is catastrophically reduced.

Specialists in the field of reproductive medicine have been offered quite a lot of ways of the so-called "build-up" of the mucous uterus. However, the most effective method has not been found.

Along with this, some clinics continue to engage in research aimed at overcoming this pathology.

As is known, the process of mucosal regeneration occurs in women throughout the reproductive (child-bearing) age. This requires a constant supply of stem cells into the basal layer. Their main sources are adipose tissue and bone marrow. From the cells of adipose tissue, the so-called mesenchymal cells, which have the capacity for further transformation, are obtained.

During the research stem cells were introduced into the endometrium. As one of the results showed, a patient who had had eleven unsuccessful attempts at conception had a pregnancy.

It should be noted that the question of the scheme of hormonal support remains unknown and also in which cases this method can be used.

However, the thickness of the endometrium may be too large. This condition in gynecology is called a hyperplastic process. As the data show, hyperplasia is almost 5% of all gynecological pathologies.

Too much thickness of the endometrium is caused by hormonal disorders against the background of diseases of the thyroid gland, ovaries, adrenals. Hyperplastic processes are detected in the mucosa in obesity, diabetes mellitus. The thickness of the endometrium may be affected by an elevated level of estrogen against a background of relatively low concentrations of progesterone. In this case, hyperplasia is due to the fact that the former contribute to the growth of the mucosa, while the second inhibits its excessive growth. Endometrium, the thickness of which is increased, can cause infertility.

Hyperplastic processes can develop at any age. The provoking factor in young patients is the development of the inflammatory process in the uterine cavity. Often, the increased thickness of the endometrium is noted in combination with endometriosis and myoma.

Hyperplastic processes in the mucosa are divided into adenomatous (atypical) and endometrial typical hyperplasia, as well as polyps of the endometrium.

Polyp is called an isolated, expanding formation in the uterine mucosa. Basically, his education occurs on the so-called leg. Polyps can be both plural and single.

It should be noted that the development of hyperplastic processes in the mucosa provokes a potential risk of cancer. At the same time there is a different probability of oncological changes occurring with different types of hyperplasia. As practice shows, the maximum it is considered at the atypical form and makes about 40%.

In addition, it should be remembered that not every hyperplasia refers to the precancerous state of the endometrium. According to the recommendations of individual experts, this state should include:

- changes in the mucosa of the adenomatous character at any age;

- glandular hyperplasia during menopause;

- glandular hyperplasia in conjunction with the development of neuroendocrine disorders at any age.