The drug "Revmoxicam": instructions for use (injections, pills and candles). Analogues and reviews about the drug

Treatment of diseases of the musculoskeletal system, removal of pain and inflammation in the joints and muscles is possible due to non-steroidal anti-inflammatory drugs, which include the drug "Revmoxicam." The instruction for this agent includes a description of the composition of all dosage forms, pharmacodynamic characteristics, indications and information about the features of use.

Description of the preparation

The main active ingredient of this drug is substance meloxicam from the oxicam group, the basis of which is enol acid. This drug has a selective effect against the mediators of the inflammatory process, which is important for protecting the digestive organs from unwanted processes.

On the drug "Revmoxicam" instruction for use describes several dosage forms that allow you to choose the appropriate method of treatment, taking into account the characteristics of the body and related diseases.

For oral administration, a tablet form with a dosage of meloxicam in one tablet of 7.5 or 15 mg is suitable. The higher-dose pills are at risk for breakage in half, which allows you to adjust the medication intake in the absence of pills of lower dosage. This dosage form is suitable for long-term treatment.

Injection form is 1% solution of the active substance, which is released in 1.5 ml in ampoules "Revmoxicam". Instructions on the degree and speed of action puts the first place, which should be taken into account when choosing a dosage form.

For rectal administration, suppositories with a dose of meloxicam 0.015 g are used. The basis of the candle is animal fat, in which the active substance is evenly distributed.

How the drug works

The anti-inflammatory, analgesic and antipyretic action of the drug "Revmoxicam" is based on the ability of the active substance to selectively slow down the processes associated with the synthesis of prostaglandin substances. It is these compounds that mediate inflammatory processes.

The drug "Revmoxicam" instructions for use characterize it as a safer drug compared to other non-steroidal anti-inflammatory drugs. This is due to the slowing down of only the enzyme cyclooxygenase type 2, resulting in reduced production of prostaglandin and prostacyclin substances responsible for inflammation. The drug has a slight effect on type I cyclooxygenase, which is why gastroprotective prostaglandins and thromboxanes are produced in the right amount and serve as a defense of the digestive system against the development of undesirable reactions.

The active ingredient of the preparation "Revmoxicam" (ampoules) describes the application instruction as a component that does not degenerate in cartilage cells and does not inhibit the production of proteoglycans, which is observed when treated with, for example, indomethacin.

The medication does not change the platelet aggregation and duration of bleeding, as occurs with the action of diclofenac and ibuprofen.

Analogues

On the pharmaceutical market, there are a number of interchangeable medicines, similar in effect and composition to the drug "Revmoxicam". The instruction of analogues is considered as synonyms, which are reproduced in the manner of the original German preparation "Movalis" of the company "Boehringer Ingelheim" in a certain dosage form.

The variety of medications based on meloxicam makes it possible for patients to be treated as European (Meloksikam-Teva, Mirlox, Meloks), and by domestic medications that vary considerably in price. Among the generic medicines of Russian production, there are "Movasin", "Lem", "Meloksikam", "Arthrozam", "Ameloteks."

A wide variety of drugs-synonyms of different manufacturing plants speaks about the wide use of medications based on meloxicam.

Why use

For the preparation "Revmoxicam" instructions for the use of injections, tablets and suppositories are recommended for the treatment of pain, inflammatory and degenerative processes in the musculoskeletal system, such as arthrosis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis.

According to the mechanism of action, this agent is suitable for treating various inflammatory processes in the human body. Not all possible indications include the medication "Revmoxicam" (candles) instruction. In gynecology the drug is widely used for the treatment of inflammatory processes of female genital organs, for example, ovaries. However, such appointment can be prescribed only by the attending physician, who will establish the dosing and duration of treatment.

Use of tablets

The drug in tableted form is intended for oral administration. Absorption of meloxicam from the digestive system occurs quickly and is 90%. Food does not affect the penetration of meloxicam through the intestinal mucosa.

Take medicine "Revmoxicam" (tablets), the instruction advises together with food to reduce the risk of developing unwanted reactions in the digestive system. The tablet should be swallowed whole, do not break it or crush it, just drink plenty of liquid. The duration of treatment and dosage of the drug depend on the severity of the disease and is determined by the attending physician.

Treatment of osteoarthritis in adults and adolescents from 15 years of age is carried out with a daily dose of 7.5 mg. If necessary, the doctor can double the daily dose.

Treatment of rheumatoid arthritis and ankylosing spondylitis in adults and adolescents from 15 years is carried out with a daily dose of 15 mg. Dosage is reduced to 7.5 mg only after receiving positive dynamics from high-dose therapy.
If there are prerequisites for the development of adverse reactions, patients are prescribed to take the drug at the lowest single dose of 7.5 mg.

Use of injections

For a more rapid action, the drug "Revmoxicam" (injections) is used, the instructions for use describe the parenteral intramuscular injection of the drug. This application is indicated for persons with diseases of the digestive tract. This is due to the fact that the stomach or intestines are not damaged by the tablets of the drug "Revmoxicam". Instructions for the use of the shots advise to enter the area of the upper outer quadrant of the buttocks, deep into the muscle.

The period of treatment and the dosage of the medicine depend on the severity of the disease and are determined by the attending physician.

For adults and adolescents from 15 years of age sets the dose of the drug "Revmoxicam" instruction for use, injections are done once a day. Typically, from 0.75 to 1.5 ml of meloxicam solution is administered. The drug "Revmoxicam" in the form of an injection can be used no longer than 5 days, and then switch to the tablet forms of this medication.

After the administration of the drug, its active substance is absorbed 100% into the systemic bloodstream, which indicates its high bioavailability.

Not all patients are allowed high doses of the drug "Revmoxicam", the instruction for the use of injections for people who have renal and hepatic insufficiency, recommends conducting with a dose of 7.5 mg meloxicam. At the same time, the indicators of these organs should be monitored in order to prevent deterioration of the condition.

If you use several forms of the drug "Revmoxicam" at the same time, it is advisable to combine injections, tablets or suppositories so that the dose recommended for daily intake is not too high.

Instructions for the use of candles

The medication can be used rectally by injecting a suppository into the rectum for further absorption of the active substance by blood vessels in the rectum and further penetration of meloxicam into the bloodstream.

For the implementation of this procedure, you need to pre-prepare by conducting hygienic manipulation. Candles "Revmoxicam" instruction for use recommends unpacking and injecting with well-washed hands, so as not to infect the infection in the anal passage.

The candles of this preparation are made of solid fat, they quickly melt in the hands, so the introduction of the suppository after opening the primary package should be immediate. The period of use and dose depend on the type of disease and degree of severity, but in any case all prescriptions are prescribed by the doctor.

Rectal application of meloxicam allows to be well absorbed into the systemic bloodstream, with a bioavailability of about 90%. A stable therapeutic content in the blood plasma occurs after 5 days from the start of therapy.

For adults and adolescents from 15 years of the "Revmoxicam" candles, the instructions for use prescribe to use no more than 1 suppository once a day.
The maximum amount of meloxicam per day should be about 15 mg, which corresponds to 1 suppository.

According to the instructions for use, rectal administration of the drug can be no more than a week, and for further treatment should be transferred to the use of tableted forms of medicament "Revmoxicam."

When you can not use the drug

It is not always possible to use medicament "Revmoxicam", the instruction for use includes a list of contraindications, in which this medication is not used.

1. With increased individual sensitivity to oxycam and other non-steroidal anti-inflammatory drugs, this drug is canceled.
2. Do not use the tablet form of the drug in patients who suffer from impaired absorption of glucose and galactose, with signs of lactase deficiency and individual intolerance to galactose molecules.
3. Treatment with the drug is contraindicated for people with peptic ulcer disease in the stomach and duodenum, with liver diseases, with heart muscle and kidney failure in severe form, to persons who underwent coronary artery bypass grafting.
4. Do not use the drug in patients who are at high risk of bleeding, especially if there was cerebrovascular or manifest gastrointestinal bleeding.
5. The drug "Revmoxicam" in the form of candles is not used in patients who have rectum diseases of various origin. Contraindication is also the inflammatory process of the rectum.
6. Pregnant and breast-feeding women, children under 15 years of age, the drug is not prescribed because of its toxic effect on the growing body.
7. The drug "Revmoxicam", injections, the instruction prohibits the use of intravenous, acceptable only intramuscular injection in the gluteal muscle.

With caution appoint the drug to patients who have bronchial asthma, cirrhosis, dehydration, diseases of the urinary system, congestive heart failure, decreased renal blood flow.

Elderly patients, people with a weakened body or who are on anticoagulant therapy should take this medicine under the supervision of a doctor.

Special care requires the treatment of the drug people who have had peptic ulcer in the stomach and duodenum and other diseases of the digestive tract in the past.

Combination with other medicines

Simultaneous combination of some drugs with the drug "Revmoxicam" can mutually enhance or reduce their effectiveness, cause unwanted reactions.

• Joint use of meloxicam and non-narcotic analgesic medication leads to an increased risk of ulcers on the mucous membrane of the digestive organs or even bleeding.
• It is not recommended to combine the preparation "Revmoxicam" with anticoagulant and thrombolytic medicines that provide antiaggregation of blood cells.
• Simultaneous reception of meloxicam and diuretics against the background of general dehydration of the body can provoke acute renal failure in such people. If from reception it is impossible to refuse, constant monitoring of kidney function is necessary .
• Simultaneous application can cause a decrease in the therapeutic effect of intrauterine contraceptives, beta-blockers, vasodilating, diuretic drugs and medications involved in the inhibition of the angiotensin-converting enzyme.
• In combination with methotrexate, the drug "Revmoxicam" is able to increase the toxic effect on blood cells, and simultaneous administration with cyclosporine leads to a negative effect on the work of the kidneys. If there is a need for such a combination, then periodic monitoring of the blood condition along the periphery and kidney function is necessary.
• The action of the drug is aimed at increasing the concentrations of lithium ions in blood plasma. The combination of colestyramine with the preparation "Revmoxicam" leads to a decrease in the time for half-elimination of the active substance.
• The action of this non-steroidal anti-inflammatory drug is aimed at changing the effectiveness in the work of tableted hypoglycemic drugs, including those containing insulin. For patients with high blood sugar levels, taking the drug "Revmoxicam" requires the control of the glucose content in the blood plasma, in order to regulate the dose of hypoglycemic medications.

Reviews about the drug

As can be seen, the range of the drug "Revmoxicam" is varied, the instructions do not describe the instructions, but it describes all the undesirable consequences from the use of this remedy, all contraindications and interactions. Such information does not mean that all adverse reactions must necessarily occur after taking medication based on meloxicam. Treatment can take place without significant undesirable effects to the body, and the therapeutic effect will be noticeable. Each organism is individual and reacts differently to different substances.

As already noted, not all indications for use are described in the instructions, but only those relating to the treatment of rheumatic abnormalities of the musculoskeletal system.

Being an anti-inflammatory drug, the drug "Revmoxicam" has found wide application for the treatment of fractures, as part of complex therapy of inflammation in chronic prostatitis, inflammatory processes in the gynecological area.

To quickly remove the pain syndrome, I recommend injecting the injections with the "Revmoxicam" preparation. Comments about the effectiveness of such injections sound ambiguous.

One patient almost immediately becomes lighter, the pain recedes, the other drug does not fit, and you need to look for a replacement.

To treat rheumatic conditions, meloxicam tablets are used, which can be taken for a long time, however, such treatment can cause digestive disorders in many people, which also requires the abolition of the medication.

There are positive reviews of the combined therapy of adnexitis, when in combination with injectable anti-inflammatory drugs, the "Revmoxicam" suppositories are used.