The drug "Mifegin", the instruction for dosing

The drug "Mifegin" is released in the form of tablets, the active ingredient of which is 200 mg of mifepristone micronized. Pharmacological medication enters the clinico-pharmacological group of anti-gestagenic drugs, increases the tone and contractility of the muscular wall of the uterus.

The drug "Mifegin" refers to synthetic steroidal anti-gestagenic drugs, inhibits the action of the hormone progesterone, does not possess gestagenic activity. Under the influence of the drug, delamination of the decidual membrane occurs and the prolapse of the fetal egg.

The drug "Mifegin", instruction for use

The drug is prescribed with a medical interruption of uterine pregnancy on terms up to 42 days; During the preparation and stimulation of labor in a normal term pregnancy.

The drug "Mifegin", the instruction for dosing

The drug is used by medical specialists in a medical institution.

For the termination of pregnancy: medication prescribed 600 mg of mifepristone micronized. 3 tablets of the drug for 200 mg the patient takes inside at a time in the presence of a doctor. After taking the drug "Mifegin", the woman should be under the close supervision of the doctors for another 2 hours.

One and a half to two days after receiving the drug "Mifegin" it is necessary by ultrasound to clarify the result, and after 8-14 days, a second examination in a clinical setting and ultrasound control are performed. Be sure to investigate the concentration of beta-chorionic hormone in order to confirm the fact of miscarriage. If it was not possible to achieve the desired result for a period of 14 days, then a vacuummask is performed with the obligatory subsequent examination of aspirate for histology.

For the preparation of births, in order to cause labor, single-dose mifepristone is administered in the amount of 200 mg, 1-well tablet in the presence of a doctor. Reconfigure mifepristone after 24 hours, again one-time 200 mg - 1-well pill in the presence of a doctor. If labor does not occur, after 48-72 hours, the condition of the birth can be examined, and prostaglandins or oxytocin are prescribed as needed.

The drug "Mifegin", the instruction: side effects

Women complain of pain in the lower abdomen, a feeling of discomfort, discharge with an admixture of blood from the reproductive organs. There is an exacerbation of chronic diseases of the uterus and its appendages. Side effect of the drug may manifest as weakness, nausea, headache, vomiting, diarrhea. Very rarely, doctors found in patients signs of hyperthermia, hives and dizziness.

In complex treatment with misoprostol, the side effect is rarely seen by the inflammatory process of the vagina, insomnia, asthenia, pain in the leg, unreasonable anxiety, anemia. Physicians sometimes had to observe a decrease in the level of hemoglobin in the blood, fainting, discharge in the form of whitecaps.

The drug "Mifegin", the instruction: contraindications

You can not prescribe the drug:

• With adrenal insufficiency;
• With renal failure in acute or chronic form;
• With hepatic insufficiency in acute or chronic form;
• With the established diagnosis of porphyria;
• After receiving glucocorticoids for a long course;
• With anemia;
• With violations of hemostasis;
• In severe diseases, syndromes and conditions associated with extragenital pathology ;
• With increased sensitivity to the drug.

Medication "Mifegin" (tablets) can not be prescribed for the purpose of interrupting pregnancy by a medicamentous method:

• At suspicion of ectopic pregnancy;
• In pregnancy, not confirmed by clinical studies;
• At pregnancy, which term exceeds 42 days amenorrhea;
• When pregnancy occurs in combination with the use of intrauterine contraceptive or after the rejection of hormonal contraception;
• With diseases of the genitals complicated by the inflammatory process;
• For smoking women who have reached the age of 35, who have not undergone a therapeutic examination.

The drug "Mifegin" can not be prescribed for the purpose of preparation and induction of labor:

• With gestosis in severe form, pre-eclampsia, eclampsia;
• With premature or delayed pregnancy ;
• With placenta previa;
• When there is a discrepancy between the fetal head and the mother's pelvis;
• At abnormal positions of the fetus;
• With bloody discharge of unclear etiology.