The drug "Concor" (tablets): from what it is used?

To improve the work of the heart and overall well-being, prescribe the drug "Concor" (tablets). From what specifically it is used and how to use the medicine correctly? Let's talk about this in the article.

Indications for use

Elevated blood pressure, chronic heart failure, angina pectoris are far from rare. And in recent years, there has been a tendency to "rejuvenate" such pathologies. With what it is connected, it is difficult to say. As a rule, such complications are preceded by various heart diseases (endocarditis, myocarditis, pericarditis), some autoimmune ailments (rheumatic fever, psoriatic and rheumatoid arthritis and others), lesions of systems and organs (liver, lungs, spleen). In order to prevent the development of serious complications of these ailments, it is necessary to treat them in a timely and adequate manner. For this purpose, the medicament "Concor" (tablets) is used. What is the use of this drug, we found out, now we will discuss the mechanism of action of the drug.

How does the "Concor" medication work?

The drug is a highly effective selective beta-1-adrenoblocker long-acting. Bisoprolol hemifumarate is the active substance of the drug (one tablet can contain 5 or 10 mg). The medicine also contains auxiliary substances: colloidal silicon dioxide, corn starch, microcrystalline cellulose, magnesium stearate, calcium hydrophosphate, crospovidone. Under the action of the drug Concor, epinephrine and norepinephrine do not reach beta-1 adrenoceptors, due to which the excitability and conductance of the myocardium are suppressed, blood pressure decreases (from the pressure of "Concor" is used most often), the heart rhythm is normalized, the coronary vessels dilate. If you take the drug in doses recommended by your doctor, then it does not affect the organs that contain beta-2-adrenergic receptors (for example, in the bronchi). High doses affect these receptors and this is manifested, first of all, by spasm of the bronchi.

Pharmacokinetics

The medicine is quickly absorbed from the digestive tract. Bisoprolol is distributed quite widely, binding of plasma proteins to this substance reaches about 30%. Part of the drug (up to 50%) is unchanged in kidneys, the rest - after decomposition in the liver to metabolites is also excreted by the kidneys.

Instructions for using the drug Concor (tablets)

Whatever the medicine was prescribed, take it in the morning once a day regardless of the meal. Razirat to powder or chew tablets is not recommended.

• Angina pectoris and hypertension. The dose of the drug "Concor" from the increased pressure is selected individually and depends on the heart rate and the patient's well-being. Usually appoint no more than 5 mg of medicament. On the recommendation of the doctor, the daily dose of the drug can be increased to 10 mg, maximum - to 20 mg.
• Chronic heart failure. With this condition, the initial dose of the drug is 1.25 mg. Gradually increase the dose to 2.5; 3.75; 5; 7.5 and 10 mg. The minimum break between the dosage increases should be 2 weeks.

Contraindications to the use of the drug "Concor" (pills)

From what and how to take the medicine correctly, it was described above, but you should also know that the drug can not be used when:

• Individual intolerance of the main and or auxiliary components, as well as other beta-blockers;
• Acute heart failure ;
• Decompensated heart failure;
• Shock states caused by cardiac disorders;
• Sinoatrial blockade;
• Severe bradycardia;
• Marked decrease in blood pressure;
• Bronchial asthma (in severe form);
• Expressed violations of the arterial peripheral circulation;
• Chronic obstructive pulmonary disease;
• Metabolic acidosis;
• Raynaud's disease.

With care use a medicament under such conditions as:

• Angina of Prinzmetal ;
• Diabetes mellitus, which is characterized by significant fluctuations in the amount of glucose in the blood;
• Diabetes mellitus (type 1);
• Restrictive cardiomyopathy;
• Severe hepatic impairment;
• psoriasis;
• Congenital heart diseases;
• Hyperthyroidism;
• Conducting desensitizing treatment in patients who adhere to a strict diet.

Finally

Those patients who took the pill from the pressure of "Concor", the reviews leave mostly positive, they indicate the high effectiveness of the drug. However, this is only if all the recommendations of the doctor are observed. In any case, appoint this medicine only a specialist who takes into account the characteristics of the body and the severity of the disease. Self-medication is unacceptable!