Pirentel - instructions for use.

Dosage form

The drug is available in two dosage forms - tablets and suspensions.

The capsule pills are yellow and risk on one side.

Composition:

Active substance:

• Pyrantel pamoate 250 mg (in 1 table).

Excipients:

• Arabic gum;
• gelatin;
• starch;
• Propylparaben;
• Methylparaben;
• talc;
• Colloidal silicon dioxide ;
• Magnesium stearate;
• Glucose sodium starch.

Pyrantel - suspension. Instructions for use include the type and composition of the suspension. The suspension is also yellow, viscous.

Composition:

Active substance:

• Pyrantel pamoate - 50 mg (in 1 ml of suspension).

Excipients:

• Saccharin sodium ;
• Sodium methyl paraben;
• Sugar sugar;
• Sodium propylparaben;
• sodium chloride;
• Sorbitol 70%;
• Sodium carboxymethylcellulose;
• Polysorbate 80;
• purified water;
• chocolate chips.

Pharmacological action of the drug "Pirantel"

The instruction says that "Pirantel" is a drug belonging to the group of anthelmintic agents. The drug can cause a neuromuscular blockade against sensitive helminths. The drug is more active in relation to Necator americanus, Ancylostoma duodenale, Enterobius vermicalaris, less active against Nrichocephalus trichiurus.

The drug, thanks to its action, is able to influence all age groups of parasites - that is, both on immature individuals and sexually mature ones, in addition, it affects individuals of any gender. But the drug can not have any effect on the larvae of individuals, especially those that are in the migration stage.

Pharmacokinetics

The drug after consumption is practically not absorbed from the digestive tract at all. The maximum concentration of the drug in the blood after a single dose is reached after 1-3 hours. Pirantel is metabolized to its metabolites in the liver and almost unchanged is excreted from the body, mostly through the intestine (93%). Another 7% can be excreted by the kidneys in the form of metabolites or simply unchanged.

Indications for the use of the drug "Pirantel"

The instruction includes 4 types of disease, in which there is a need for taking this medicine.

• Trichocephalus;
• Necropsy;
• Ankylostomidosis;
• Ascaridosis.

Dosage of the drug "Pirantel", the use of which must be done only after eating, should be established by the doctor, based on the patient's age data, weight, as well as contraindications and the possibility of side effects.

In the treatment of enterobiosis, it is necessary to treat simultaneously all persons living on the same living space. This measure is aimed at excluding the possibility of re-infection, for example, from one of the family members. After treatment, it is necessary to make tests to check the presence of parasites in the patients' body.

Side effects

Possible side effects of the drug from the gastrointestinal tract:

• diarrhea;
• nausea;
• anorexia;
• Vomiting;
• An increase in the activity of liver transaminases.

Possible side effects of the drug from the peripheral and central nervous system:

• Hallucinations;
• headache;
• Dizziness;
• Confusion;
• insomnia;
• drowsiness.

Other side effects:

• temperature increase;
• skin rash.

Contraindications of pyrantel preparation

Instructions for the drug include only the main contraindications to the drug:

• Myasthenia gravis;
• Sensitivity to pyrantel;
• pregnancy;
• lactation.

The drug should be used with caution in liver failure in a patient's history.

Do not administer laxatives after taking the drug.

Children under 6 years of age this drug is administered with great care.

Drug Interactions of Pirantel

The instruction says that when applying pyrantel simultaneously with piperazine, the effect of the second is noticeably weakened.