Medication 'Neo-Penotran' (candles). Instructions

The drug "Neo-Penotran" (candles) is used in gynecology. The agent includes miconazole nitrate and metronidazole.

The Neo-Penotran (candles) instruction is recommended for local treatment of bacterial vaginosis, trichomonas vulvovaginitis, vaginal candidiasis, and vaginal infections of mixed type.

Suppositories are contraindicated in severe disorders of hepatic function, pathologies of the nervous system (peripheral and central), hypersensitivity, disorders of hemopoiesis (hematopoiesis). Medication "Neo-Pentotran" (candles) instruction does not allow for the appointment of pregnant women (in the first trimester), girls under fourteen, as well as virgins.

Suppositories must be injected deep into the vagina. Introduction is carried out with the help of special fingertips (disposable). The drug "Neo-Penotran" (candles) instruction recommends the use once a day. Duration of therapy from seven to fourteen days.

With relapsing or resistant to other medications, vaginitis is recommended to be administered by suppository in the morning and evening. The duration of application is two weeks.

Use the drug "Neo-Penotran" (candles) instruction during pregnancy does not prohibit (except the first trimester). However, the appointment should take into account the ratio of expected benefits to pregnant women and the potential hazard to the fetus.

During therapy, lactation should be stopped. Resume breastfeeding is allowed after two or four days after the introduction of the last suppository.

The use of the drug may trigger a number of adverse reactions. Side effects include irritation in the vagina, itching, burning. Due to the fact that vaginitis is accompanied by inflammatory processes, irritation may increase after the application of the first suppository or on the third day of therapy. As practice shows, these unpleasant symptoms are eliminated after drug cancellation. If there is severe irritation, therapy should be stopped.

When applying suppositories "Neo-Pentotran", abdominal pain, dry mouth or smack of metal, vomiting, deterioration of appetite, diarrhea or constipation are possible.

In some cases, cramps, peripheral nephropathy (against prolonged use of the drug), psychoemotional disorders, dizziness, movement disorders, headache are likely.

Probable skin rashes, itching.

It should be noted that the Neo-Penotran (candles) remedy (reviews of many patients point to this) are well tolerated. These negative reactions are extremely rare. Many women prefer the Neo-Penotran Forte (candles) medicine. The instruction does not indicate any significant differences between the preparations.

Drug Interactions

Medication "Neo-Pentotran" when interacting with alcohol provokes disulfiram-like reactions.

Active components of suppositories can enhance the effect of indirect anticoagulants.

With the use of the drug "Phenytoin" along with the drug "Neo-Penotran", the level of the first in the blood increases, while the content of metronidazole (the active component of vaginal suppositories) decreases.

With simultaneous use with the drug "Disulfiram", changes in the nervous system (psychotic states) can develop.

The drug "Cimetidine" helps to increase the concentration in the blood of metronidazole. This increases the likelihood of neurological side effects.

Means "Neo-pentotrans" increases the toxicity of lithium.

When using suppositories of vaginal concurrent with the drugs "Terfenadine" and "Astemizol", the concentration of the latter in the blood increases.

Before using Neo-Pentotrans, read the summary and consult with the doctor.