HealthMedicine

DTP vaccine

The DTP vaccine is a combination vaccine directed against pertussis, diphtheria and tetanus (adsorbed pertussis-diphtheria-tetanus vaccine).

At one time, the introduction of DTP into the calendar of preventive vaccinations allowed a hundredfold reduction in the number of cases of development of the corresponding pathologies (diphtheria, tetanus, pertussis), complications and fatal outcomes from them. That is why the question "is it necessary or not to vaccinate?" Is a fundamentally illiterate question. The question should be as follows: "What vaccine should I vaccinate?".

An antianxiety vaccine after the course of vaccination forms an immunity in the human body lasting from five to seven years. The DTP vaccine, and in particular its antitetanus and antidiphtheria components, form a stable immunity lasting about ten years. As a result of the weakening (after the indicated period of time) of immunity, a planned revaccination is necessary.

The scheme by which the DTP vaccine is introduced

The first vaccination is given to the child at three months, then at four and five months. The first revaccination is carried out at 1.5 years, the next one at 6 years (this revaccination is done not by DTP, but by ADS-M, since there is no need for booster vaccination against pertussis). The third revaccination is carried out exclusively by AD-M anatoxin at the age of eleven. The fourth - in sixteen years. Subsequent revaccinations are carried out at intervals of ten years to sixty-six years, inclusive.

The DTP vaccine is administered intramuscularly. The quality of the vaccine (that is, the minimal probability of developing side effects and the maximum level of stimulation of the production of the necessary antibodies) depends primarily on the degree of purification of the vaccine from impurities.

DTP vaccines are distinguished depending on the level of their reactogenicity (that is, the ability to cause this or that reaction in the body when the drug is administered). The least reactogenic is the cell-free vaccine, which is Infanriks. The minimum reactogenicity is associated, first of all, with the absence of microbial cell impurities in the vaccine composition. This vaccine consists exclusively of the protein necessary for the development of immunity of a high degree of purification. Whole-cell vaccines, such as DTP and Tetracoc, in their composition contain the entire microbial cell as a whole, which creates a high reactogenicity. The human body reacts to foreign agents with various post-vaccination reactions and complications. Due to the development of postvaccinal reaction with the introduction of the whole-cell DTP vaccine, it is necessary to use anti-inflammatory, antipyretic and analgesic drugs.

Thus, the DTP vaccine imported - England's Infarriks has established itself as the best DTP vaccine currently. A high degree of purification provided the absence of protein impurities and various microbial fractions in the formulation. In addition, this vaccine uses the safest preservative - 2-phenoxyethanol.

As a result, the question: "What is the best vaccine for DTP?" The answer is obvious.

The best is the vaccine that went through the highest degree of purification. At present, such a vaccine is Infanriks. The next following in terms of the level of reactogenicity is the Russian tetracoc vaccine, which is whole cell.

It is also worth mentioning that in order to reduce the number of complications and adverse reactions, it is important to observe the schedule of vaccinations, as well as the detection of indications and contraindications to vaccination. In addition, early specialized preparation of the child's organism for vaccination and revaccination is carried out.

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