"Dimexid" (gel): indications for use, instructions, analogues, reviews

Transdermal administration of the drug is considered to be an effective and safe method of treating patients. This is the way to introduce a unique organic solvent - dimethyl sulfoxide, which perfectly penetrates through the epithelial cells into the body. It also enhances the transfer of a variety of active components through the skin and increases their effectiveness.

Description of the preparation

The drug "Dimexid" is a gel (the photo is shown below), which is one of the medicinal forms of the dimethylsulfoxide substance. It has an anti-inflammatory and analgesic effect to relieve the pain syndrome associated with diseases of the skeleton and muscles, and is struggling with skin problems.

The drug "Dimexide" is made in the form of a colorless transparent gel, which can have a yellowish tinge. Active substance causes a weak specific smell. Available in aluminum tubes of 30 g and 40 g, packed in cardboard packs.

Active substance and dosage

For the preparation "Dimexid", gel, the instruction for use describes two dosages: with a content of dimethyl sulfoxide of 25 g and 50 g in 100 g of the drug mixture. The remaining mass of the medicament is formed by auxiliary components, which make it possible to preserve the gel-like structure.

How it works

Due to the ability of dimethylsulfoxide to actively penetrate the biological membrane of the skin and mucous membranes, the drug "Dimexide" (gel) is used externally.

The active substance from the skin quickly enters the blood vessels and spreads to all organs along the bloodstream. It is proved that after five minutes dimethylsulfoxide is already present in the blood plasma, and the presence of a specific taste in the oral cavity indicates irritation of the taste receptors with this substance.

Its action is based on the inactivation of hydroxyl radicals, enhancement of metabolic processes in the inflammatory region, fibrinolytic properties.

Antiseptic influence is carried out due to the ability to penetrate into the shell of microorganisms and to change their resistance to antibacterial agents.

Dimethyl sulfoxide has an analgesic and anesthetic effect at the site of application. This is possible due to the fact that excitatory impulses are conducted to peripheral nerves at a lower rate.

What heals

For the drug "Dimexid" (gel), indications for use are selected in accordance with the characteristics of its active substance. It is mainly used for complex treatment of such diseases as arthritis rheumatoid, ankylosing spondylitis, osteoarthritis with periarticular tissue damage, sciatica, systemic scleroderma, erythema nodosum, erysipelatous inflammation, edematous condition, sprains, infiltrates in traumas and inflammatory processes, purulent wounds, Trophic and burn ulcers, acne.

The drug is applied to the affected areas with eczema, furunculosis, thrombophlebitis, pyoderma.

It is used to treat dental diseases associated with inflammatory processes in the maxillofacial zone, in the salivary glands, with arthritis and osteoarthritis in the temporomandibular joint.

For the drug "Dimexid" (gel), the use is possible with pulpitis, periodontitis, periodontitis.

Mode of application

The drug is used as a skin, making appliques. A thin layer of gel 50% is applied to the affected skin in the face of the head, and 25% of the drug is intended for the mucous membranes. Then the medication is easily rubbed over the diseased surface and left for 15 minutes. After that, the remnants of the medicine are washed off with water. The application of the gel is carried out 2 to 3 times a day, the course of treatment lasts from 10 to 15 days.

For the treatment of diffuse streptoderma and eczema, with local analgesia of pain syndromes, 50% of the drug is used, from which compresses are applied to the affected area. Make a napkin of 4 layers of gauze, which is applied a thick layer of gel. Then it must be applied to the affected area and kept for 20 to 30 minutes. Cover the napkin with a polyethylene film and a cotton cloth.
The number of compresses varies from 2 to 3 times a day.

For complex treatment of thrombophlebitis, the drug "Dimexid" (gel) and heparin ointment is used simultaneously 2 or 3 times a day for two weeks.

Reuse is possible only after 10 days.

Children can be appointed only from the age of 12.

How it interacts with drugs

Dimexide (gel), thanks to the ability of dimethylsulfoxide to enhance the transfer through the biological membranes of many active compounds and increase their effectiveness, improves the therapeutic effect of medicines during combined therapy.

With simultaneous application increases the rate of absorption and the action of insulin and ethyl alcohol.

You can combine with drugs containing heparin, antibacterial compounds, non-steroidal anti-inflammatory components.

The gel is used to increase the sensitivity of microbial cells to the action of chloramphenicol, aminoglycosides, beta-lactam antibiotics, griseofulvin, rifampicin.

Dimethyl sulfoxide exerts a sensitizing effect on the body with respect to medicinal products for general and local anesthesia.

Since the drug may enhance the toxic properties of other drugs, caution should be exercised in combination therapy.

Features of treatment

Before using Dimexide (gel) medication, the instruction sheet recommends checking the patient for intolerance of the drug. Usually it is determined by a drug test.

The place of application of the gel is the back surface of the wrist, but not the whole surface of the skin, but a small part of it. Sign of increased hypersensitivity to the components of the drug is a sharp redness of the skin and itching. In this case, the treatment should be abandoned.

When you can not use

In addition to hypersensitivity, there are a number of other conditions in which the drug "Dimexide" (gel) is contraindicated.

They include insufficient kidney and liver activity in severe form, angina pectoris, heart muscle infarction, severe atherosclerosis.

With such eye diseases as cataract and glaucoma, dimethylsulfoxide is not prescribed.

Contraindication is pregnancy and lactation, and if necessary, the treatment of the child is transferred to artificial nutrition.

Unwanted consequences

The instructions attached to the Dimexide preparation (gel) contain information on side effects. Often this remedy does not cause undesirable consequences, but in some patients erythema, itchy dermatitis, dry skin may appear. It rarely develops bronchospasm.

One of the drawbacks of dimethylsulfoxide is the presence of an unpleasant specific odor, which remains in the room for a long time. It is his poor tolerance of some patients, which is the cause of nausea and vomiting.

Similar drugs

In the pharmaceutical market, there are many similar products based on dimethylsulfoxide. The drug "Dimexid" (gel), analogues of this drug have the same active substance, but different auxiliary components. Such a composition makes them interchangeable.

The Russian manufacturer of gel "Dimexid" is the enterprise of OOO "Farmamed", St. Petersburg. The drug for external use is available only in one dosage - 25%. It is used as an anti-inflammatory agent.

In two dosages, 25 mg and 50 mg per 1 g, there is a Belarusian gel "Dimexid." Produced by the Republican Unitary Enterprise "Belmedpreparaty".

Another similar Belarusian remedy is the drug "Dimexide-FT". It is produced by LLC "Pharmtechnology" in two dosages, 250 and 500 mg each. Refers to the anti-inflammatory drugs that have an analgesic and pronounced antimicrobial effect.

There are a number of combination drugs that include several active components, including dimethylsulfoxide. The pharmacotherapeutic effect of such medications may differ.

One such drug is the German drug Dolobienė, manufactured by Merkle GmbH in the form of a gel for external use. It contains sodium heparin at a dose of 50 IU, dexpanthenol in an amount of 25 mg and 150 mg of dimethylsulfoxide. Refers to preparations that have an antithrombotic and regenerative effect.

A multi-component agent with an irritating and anesthetic effect is the "Capsicam" ointment. It contains benzyl nicotinate, nonivamide, turpentine turpentine, racemic camphor, dimethylsulfoxide. The presence of five active components makes it possible to actively combat joint and muscle pain. It is produced by the Estonian company "Tallinn FZ".

The Ukrainian preparation "Khondrasil", an ointment for external use, contains 50 mg of chondroitin sodium sulfate and 100 mg of dimethylsulfoxide. Used for degenerative-dystrophic lesions of joints and skeleton. It is produced by the Kiev enterprise PJSC "Farmak".

Patient's opinion

Before using the medicine for treatment, doctors are advised to get acquainted with the information that is contained on the preparation "Dimexid" (gel) instructions for use. Comments on the effectiveness and safety of dimethyl sulfoxide are mostly positive.

The medicine usually begins to act immediately after application to the diseased area, whether it is inflammation in tension, bruise, burn or arthrosis. Timely use of the drug will prevent the formation of bruises in limb injuries.

If you start to treat the wound with wounds, which slowly heal or fester, then their quickest tightening takes place, pus is removed.

In obstetrics, it is used in the form of compresses on the chest with stagnant milk in the ducts. The disadvantage of this treatment is the refusal to breastfeed during therapy, since dimethylsulfoxide can affect the development of the baby.

In cosmetology, the drug "Dimexide" is used to treat skin diseases associated with acne, furunculosis or eczema. There are recommendations for the preparation of various hair masks with the addition of dimethylsulfoxide as a conductor of the drug. After several such procedures, the result will be obvious. Hair will become strong, lush, a healthy shine will appear.

Catarrhal diseases, in which there is a cough, for example, tracheitis, ARI or bronchitis, can be treated with compresses from the gel. Such manipulations will be effective for getting rid of sinusitis.

But not everyone can like the smell of Dimexide. Gel reviews are described as a remedy that smells too strong. Negative responses are mainly related to the garlic aftertaste that is present in the mouth after the drug is applied to the skin. Such a smell can cause nausea, and in hypersensitive people, bronchospasm is possible. In this case, the doctor must choose another treatment.

Many patients note that the action of the Dimexid gel is simply invaluable, the main thing is to use it correctly.