Dexamethasone - instructions for use.

Drug form of the drug "Dexamethasone"

The instruction includes reduced information on dosage forms. The drug is available in the form of eye drops, that is, whitish suspension. Presence of a resuspended deposit is possible.

Composition:

Active substance

• Dexamethasone - 1 mg (in 1 ml of suspension)

Excipients:

• Sodium chloride
• Dinuria phosphate dodecahydrate
• Hypromellose
• Polysorbate
• Citric acid monohydrate
• Benzalkonium chloride
• Dihydrate edetate dihydrate
• Purified water

In addition, it is possible to release the drug in other dosage forms.

Pharmacological action of the drug "Dexamethasone"

The instruction says that the medicine belongs to the SCS, suppressing the functions of tissue macrophages and lymphocytes, which the drug also limits in the ability to migrate to the area of inflammation. The drug disrupts the possibility of macrophages to phagocytosis, and in addition to the formation of interleukin 1.

Has a vasectonic effect, being in close proximity to the vessels. Suppresses the capture of glucose by fat cells, thereby activating lipolysis. But, because of the increase in the amount of insulin, lipogenesis is stimulated, which can lead to the accumulation of fat.

Indications for the use of the drug "Dexamethasone"

The use of the drug inside with the following diseases:

• Thyroid acute and subacute forms
• Addison-Birmer disease
• Progressive ophthalmopathy (due to hypothyroidism)
• Hypothyroidism
• Rheumatoid arthritis
• Bronchial asthma
• Autoimmune anemia
• Hypoplasia and aplasia in hematopoiesis
• Thrombocytopenia
• Congenital adrenogenital syndrome
• Serum sickness
• Agranulocytosis
• Pemphigus
• Acute erythrodermia
• Malignant tumors
• Cerebral edema

For parenteral administration of the drug:

• Radiation damage of the brain
• Cerebral edema
• Encephalitis
• Hemorrhage in the brain
• Meningitis
• Asthmatic status
• Shock of different genesis
• Dermatosis
• Bronchospasm
• Edema Quincke
• Acute anaphylaxis on drugs
• Pyrogenic reactions
• Serum transfusion
• Thrombocytopenia
• Hemolytic anemia
• Agranulocytosis
• Lymphoblastic leukemia
• Infectious diseases
• Spicy groats
• Insufficiency of the adrenal cortex
• Osteoarthritis
• Arthritis
• Compression neuropathy
• Tendovaginitis
• Bursitis
• Styloiditis
• Epicondylitis
• Pleiraptocular periarthritis

For use in ophthalmology:

• Keratite
• Conjunctivitis
• Irit
• Keratoconjunctivitis
• Blepharoconjunctivitis
• Iridocyclitis
• Episcleritis
• Blepharitis
• Sclerite
• Sympathetic ophthalmia

Side effects of the drug "Dexamethasone"

The instruction includes data on side effects with respect to various body systems and other dosage forms of the drug "Dexamethasone" - tablets. The instruction is presented in a shortened form.

Possible side effects from the use of the drug on the part of the endocrine system:

• Ithenko-Cushing syndrome
• Children may delay sexual development
• Diabetes
• Decreased glucose tolerance
• Oppression of adrenal function

From the metabolism of the body:

• Hypocalcemia
• Excretion of calcium ions
• Negative nitrogen balance
• Hypernatremia
• Increased sweating
• Weight gain
• Hypokalemia

From the side of the central nervous system:

• Euphoria
• Disorientation
• Delirium
• Depression
• Manic-depressive syndrome
• Hallucinations
• Increased intracranial pressure
• Insomnia
• Nervousness
• Anxiety
• Vertigo
• Dizziness
• Convulsions
• Headache

On the part of the CAS:

• Bradycardia
• Arrhythmia
• Chronic heart failure
• Hypercoagulation
• Increased blood pressure
• Thrombosis

From the digestive tract:

• Vomiting
• Nausea
• Stomach ulcer
• Erosive esophagitis
• Perforation of the digestive tract
• Gastrointestinal bleeding
• Impairment of appetite
• Hiccups
• flatulence

Contraindications for the use of the drug "Dexamethasone"

The instruction does not include exhaustive data on the contraindications of the preparation, for more detailed information it is necessary to refer to the official source. The main contraindication for taking is sensitivity to dexamethasone. In addition, there may be contraindications associated with infectious diseases, inflammations, etc.