Clotrimazole tablets - a description of the drug

Any fungal lesion is rather unpleasant, because, firstly, it is sometimes difficult to diagnose, and secondly, it is difficult to find a suitable remedy for treatment.

Clotrimazole, whose tablets are intended for vaginal use, are based on an antifungal substance, the same name with the name of the drug itself (a dosage of 100 or 200 or 500 mg). The excipients include lactose, aerosil, corn starch, soda, tartaric acid, magnesium stearate.

Pharmacological characteristics

Clotrimazole is an imidazole derivative. This antifungal agent is a fairly broad spectrum. The effect of taking the drug is achieved through a violation of the synthesis of ergostin, which enters the cell membrane of fungi. Taking clotrimazole causes changes in the structure of the membrane, its properties and cell lysis. Dermatophytes, mold fungi, pathogens Pityriasis versicolor and sciatica, as well as yeast fungi, Candida and Torulopsis glabrata are especially sensitive to the drug. Antimicrobial action against staphylococci and streptococci, as well as gram-negative bacteria

Clotrimazole tablets - indications for use

- the presence in the smears of traces of genital infection (yeast fungi of the genus Candida and Trichomonas);
- diagnosis of vulvovaginal candidiasis, trichomoniasis;
- Genital superinfection from bacteria with sensitivity to clotrimazole;
- prevention before gynecological procedures.

Clotrimazole, whose tablets should be used strictly according to the instructions, is used as follows.

When treating vaginal infection, it is customary to prescribe 1 tablet once a day (mostly in the evening). The tablet should be administered as deep as possible directly into the vagina. The course of treatment is usually about 6 days, if necessary, the term is doubled.

Clotrimazole tablets - side effects

There may be spasms in the lower gastrointestinal tract, rash, generalized erythema. There may also be local reactions: tingling and burning, reddening of the vaginal mucosa.

Tablets vaginal clotrimazole - contraindications

Contraindication to taking the drug is hypersensitivity to the main active substance - clotrimazole, as well as the I trimester of the ongoing pregnancy.

Special Recommendations

It is necessary to pay attention to the fact that the treatment of infection must necessarily be passed at both sexual partners simultaneously. Only this way it will be possible to prevent its further spread, otherwise there will be a mutual infection, and the treatment will not have any effect. Such a diagnosis, like trichomoniasis, suggests that other drugs with systemic action are prescribed in the course of treatment with clotrimazole.

It is not recommended to use tablets during menstruation. With the oral method of taking the drug may develop anorexia, vomiting, nausea, gastralgia and other disorders, liver damage, hallucinations, pollakiuria, skin allergic reactions. If at least one of these listed reactions is manifested, immediately take an activated charcoal to cleanse the body and seek medical help from a doctor.

Clotrimazole is poorly compatible with polyene antibiotics (amphotericin, nystatin, natamycin, etc.), it lowers their effect. Simultaneous reception with nystatin leads to a decrease in the effectiveness of both drugs. Strengthen the effect of the drug can propyl ester of ordinary para-hydroxybenzoic acid (high concentrations). Dexamethasone has the opposite effect. Tablets are stored in dry, sheltered from light places. The air temperature should be within 5 ° С-25 ° С. Children should be excluded from the drug. The useful life of Clotrimazole is 3 years.

Thus, Klotrimazol tablets , which are mostly positive reviews , are an excellent remedy against fungal lesions and really give an effect.