Prick "Cortisone": instructions for use, a description of the drug, feedback

Unfortunately, inflammatory diseases of various organs and systems can hardly be considered a rarity. Modern medicine offers a lot of drugs that can fight inflammation. And in some cases, doctors prescribe patients a "Cortisone" shot. This drug not only inhibits the development of inflammation, but also has pronounced analgesic properties.

So what is this medicine? How does it affect the body? How are the injections performed correctly? Is the therapy associated with any complications? Many patients are looking for answers to these questions.

Composition and form of release

The drug "Cortisone" is available in the form of a suspension for intramuscular injection. In the pharmacy you can buy glass bottles containing 5 ml of solution. The main active substance of the drug is cortisone in the form of acetate - a synthetic glucocorticosteroid, which has anti-inflammatory properties. The concentration of the active component is 2.5% (in one ml of the suspension contains 0.025 g).

By the way, pharmacies also sell tablets, ointments for the skin and mucous membranes, which contain cortisone.

What are the properties of the medicine?

Cortisone affects the metabolism of proteins and carbohydrates. For example, it reduces the total amount of protein in the plasma, enhances the breakdown of protein elements in muscles, but, at the same time, activates protein synthesis in the tissues of the liver and kidneys. Cortisone also controls the process of cleavage of amino acids in the liver, indirectly affects the processes of the exchange of nucleic acids.

Also, cortisone, like other glucocorticosteroids, affects the metabolism of carbohydrates, boosts the intake of glucose from the liver into the bloodstream, accelerates the synthesis of certain aminotransferases, stimulates the formation of carbohydrates from amino acids obtained as a result of protein breakdown. Thus, the level of glycogen in the muscles and liver rises, the absorption of carbohydrates in the intestine improves, and glucose tolerance decreases.

This substance inhibits the synthesis of hyaluronidase, inhibits the synthesis of connective tissue elements, reduces the permeability of capillaries, suppresses the development of allergic reactions, delays sodium and speeds up the process of removing potassium from the body and the formation of higher fatty acids.

In what cases is the drug used? Indications for injection

Many patients are interested in the question of when it is advisable to use the drug Cortisone? What helps it? In fact, there are many indications for the use of the drug:

• Rheumatoid arthritis and rheumatism;
• Collagenoses (diseases accompanied by affection of blood vessels and connective tissue);
• bronchial asthma;
• Infectious mononucleosis;
• Some forms of leukemia;
• Neurodermatitis, eczema, some other skin inflammatory and allergic diseases;
• Insufficient adrenal function ;
• Hemolytic anemia;
• Glomerulonephritis;
• Viral hepatitis;
• Collapse and shock of various origins.

The drug "Cortisone": instructions for use

This drug of hormonal origin is quite powerful, so its unauthorized use is strictly contraindicated. Only the attending physician after a thorough examination can prescribe injections of Cortisone medication. The instructions for use contain only general information. Dosage, treatment and duration of therapy are determined strictly individually.

The suspension can be administered intramuscularly or taken internally. If it is a question of oral intake, the recommended dose for patients is 0.1-0.2 g of active substance per day, which need to be divided into 3-4 doses. As the main symptoms disappear, the dose is reduced to a minimum of 0.025 g. The drug lasts about 6-8 hours.

Intramuscularly administered 0,02-0,05 g per day. If necessary, this amount is divided into two times: Cortisone injections are done at intervals of 8-12 hours. The effect lasts about 12 hours.

A shot of "Cortisone" is made by a paramedic in a hospital. The patient should be under the constant supervision of doctors, since there is a risk of developing adverse reactions. Treatment "Cortisone" is also carried out in pediatrics - the daily dose is determined depending on the age and severity of the child's condition.

The maximum daily dose of active substance for adults is 0.15-0.3 g.

Are there any contraindications?

Undoubtedly, an important issue is whether this tool has any limitations in its application. The drug "Cortisone" can not be used in every case. Contraindications to his appointment are:

• Severe forms of hypertension, which are accompanied by a persistent rise in blood pressure.
• Recently transferred operations.
• Diabetes.
• Insufficiency of blood circulation of the third stage.
• Elderly age.
• Ulcerous lesions of the digestive tract.
• Active form of tuberculosis.
• Syphilis.
• Viral and fungal diseases.
• Serious disorders in the kidney and liver.
• Pathologies of the thyroid gland.
• Open angle glaucoma.
• Osteoporosis (against the background of taking glucocorticosteroids may worsen conditions).
• Hypersensitivity to any of the constituent components of the drug.
• Recently suffered myocardial infarction.
• Illness of Itenko-Cushing.

The injection of "Cortisone" is also contraindicated in women during pregnancy. If it is a question of the lactation period, during the therapy breastfeeding should be interrupted. Childhood contraindication is not, but apply "Cortisone" in pediatrics very carefully.

List of possible side effects

Like virtually any hormone, the drug "Cortisone" can lead to the development of some adverse reactions, including serious ones:

• A variety of allergic reactions, including swelling, rashes, skin redness, hives, Quincke's edema, less often - anaphylactic shock.
• The injection of "Cortisone" may be accompanied by the appearance of swelling and redness at the injection site.
• The Itenko-Cushing syndrome, which is accompanied by an increase in body weight, increased fragility of bones and a decrease in sexual function.
• Hirsutism is excessive hair in women.
• Acne.
• Osteoporosis and spontaneous bone fractures as a result of weakening of bone tissue.
• All sorts of mental disorders.
• Hemorrhagic pancreatitis (inflammation of the pancreas, which is accompanied by severe bleeding).
• Ulcer disease of the digestive tract.
• Perforation of an unrecognized ulcer.
• Bleeding in the digestive tract.
• Increase in blood pressure.
• Atrophy of muscles as a result of protein breakdown.
• Steroid diabetes mellitus.
• Arrhythmia, heart failure.

It is worth noting that the above complications in the study were observed only in the case of prolonged use of large doses of the drug (more than 0.1 g of cortisone per day). Several injections are unlikely to cause such serious disturbances in the body. Nevertheless, if during the therapy you notice any worsening, it is worth immediately informing the doctor about them.

Drug analogues

For some reason, not every patient is entitled to the drug "Cortisone". Analogues of it exist in the modern pharmacological market, in the form of injections, tablets, creams, ointments, etc. In particular, modern medicine uses such drugs as Betamethasone, Prednisolone, Mezipredon, Dexamethasone and Hydrocortisone. " All these medicines have approximately the same properties as Cortisone. But, since they act on the body with varying intensity, only the attending physician can choose a substitute.

Medicinal product "Cortisone": price

For many patients, the cost of a medicine is an important criterion. So how much will the Cortisone remedy? The price will depend on many factors, including your chosen pharmacy, city of residence, manufacturer, etc. One 5-ml bottle costs about 180-210 rubles. It is worth considering that for a full course of treatment you will probably need more medicine - this information will need to be clarified by the doctor. And you need to consider that in some cases, one cortisone is not enough, we need additional drugs.

Reviews of patients and doctors

Of course, every person knows that you can get a lot of useful information by getting familiar with the opinions of specialists and reviews of patients who have already been treated. Many people do notice a significant improvement after a series of injections. Moreover, a significant reduction in pain and other discomfort is observed after the first injection. Undoubtedly, there is information about the development of side effects in patients, but these cases are not so common. And the advantage of this solution is the relatively affordable cost.

The doctors themselves also speak well about the medicine. On the other hand, Cortisone, in comparison with other glucocorticoids, often causes complications. That is why modern doctors increasingly appoint analogues of a new generation of drugs that have a milder effect on the body.