Preductal MB - product description

The drug "Preductal MB" is a tablet that is coated with a special coating. The composition of these tablets includes trimetazidine dihydrochloride, the content of which in one tablet is thirty-five milligrams.

It is a preparation of an antianginal pharmacological action. It is able to normalize the process of energy metabolism of cells that have been exposed to such phenomena as hypoxia and ischemia. In addition, "Preductal MB" helps to avoid a decrease in the level of intracellular ATP. That is, this medical preparation acts in such a way as to ensure the proper, normal operation of the membrane channels, the transfer of sodium ions with potassium through the membranes. It also promotes the preservation of cellular homeostasis.

The substance trimetazidine leads to a slowdown in the oxidation of fatty xylitol. This is due to the selective inhibition of 3-ketoacetyl-CoA-thiolase. Due to this process, there is an increase in glucose oxidation, conjugation of glycolysis and oxidative decarboxylation is restored. Thus, protection against such dangerous diseases as ischemia and myocardial infarction is provided.

Laboratory experiments were conducted on animals, the results of which showed that the substance trimetazidine supports cardiac metabolism during ischemic episodes, as well as the metabolism of neurosensory organs. The drug "Preductal MB" is able to reduce the content of acidosis in cells, reduce the changes in transmembrane ion fluxes that occur in a person with ischemia.

Clinical studies have shown that people with heart disease, including angina pectoris, felt an increase in the coronary reserve. It was due to him that the development of ischemic disease, which was caused by excessive physical exertion, slowed down. This slowdown occurred on the fifteenth day of therapy. The use of the drug caused the limitation of sudden jumps in blood pressure without significant changes in the heart rate. The drug "Preductal MB" helps to reduce the frequency of angina attacks, significantly reduces the patient's need to take nitroglycerin, improves the function of contracting the left ventricle in those who suffer from coronary artery disease.

Tablets Preductal is prescribed for long-term therapy of coronary heart disease, for preventive purposes, to avoid stenocardia attacks, for the treatment of vestibular disorders that are ischemic in nature (for example, dizziness, hearing loss, tinnitus). Also, "Preductal MB" should be taken with chorioretinal vascular disorders that contain an ischemic component.

It is extremely important to know how to take this medicine correctly. Qualified specialists always prescribe a certain norm of taking tablets. So, as usual, the drug is taken one tablet twice a day. The tablet should be taken during the meal - at breakfast and at dinner. The course of treatment doctors set individually.

The drug may have some side effects. It is extremely rare, but there are side effects such as nausea and vomiting. There may be an allergic reaction to the tablets. Do not use this medication for people who are hypersensitive to the drug. It is not necessary to apply it to pregnant women, since clinical studies of its effect on future mothers have not been conducted. In addition, trimetazidine can be excreted in a woman with breast milk. Therefore, it is better not to breast-feed the baby.

The analogue of Preductal is the preparation "Rimecor".