"Ovipol Clio" candles: reviews, instructions for use, indications, analogues

Violation of the hormonal background can be observed at any age. The reasons for the lack of hormones can be very diverse and sometimes it is not so easy to fix them. It remains only to fight in all possible ways with consequences that, if not taken, can be serious. When estrogen deficiency is often prescribed vaginal suppositories for the microflora "Ovipol Clio". Let's consider more in detail this preparation, what indications and contra-indications, what patients' reviews are.

Composition of the preparation and form of release

"Ovipol Clio" - candles (reviewed below), which contain the main active ingredient - is estriol. Auxiliary components are a composition of semisynthetic glycerides. They do not come into contact with the active substance, but facilitate the introduction of suppositories.

Chemical-pharmaceutical factory "Akrihin" produces a drug in the form of vaginal suppositories. They are white with a yellowish tinge. In the packaging of cardboard there are 15 suppositories.

The effect of estriol

After entering the body, the active substance is quickly released and begins to exert its therapeutic effect on the pelvic organs of the woman:

• Affects the revascularization of epithelial tissue.
• Estriol (candles with it are very effective) promotes the compaction of epithelial tissues.
• The number of surface cells increases.
• Synthesis of cervical secret is stimulated.
• With atrophy, the epithelium regenerates more quickly and regenerates.
• The acid-alkaline balance comes back to normal.
• Vaginal candles for microflora are simply irreplaceable, they quickly restore it.
• Candles improve the blood supply of tissues.
• The risk of developing the inflammatory process decreases.

Also the candles have the following action:

• Affect the positive or negative relationship between the pituitary gland, the hypothalamus and the sexual cycle of a woman.
• As a result of the use of candles, the amount of cholesterol that is simply needed for the synthesis of sex hormones increases.
• Improves glucose metabolism and increases the sensitivity of receptors to insulin.
• The function of blood coagulation comes to normal.
• The active substance of the candles stimulates the functions of the endocrine glands.

The use of candles has its advantage over hormonal tablets, because the growth of estrogen is carried out smoothly, which significantly reduces the risk of oncology.

Indications for use of the drug

"Ovipol Clio" - candles (reviews confirm this), which have proved effective in the treatment of the following pathologies:

• Atrophic processes of the epithelium of the urogenital system, which are provoked by a lack of estrogens.
• In the preparatory period before surgery or during recovery from it.
• If the smear produces ambiguous results, candles are prescribed to clarify the diagnosis and a week later they do a second analysis.
• Stem Colpitis.
• To eliminate dryness of the vaginal mucosa.
• As a prophylactic for relapses of diseases of the genitourinary system.
• To normalize the microflora of the vagina.
• In the preparatory or recovery period with vaginal plastic.
• Candles effectively eliminate the itching of the vulva and help get rid of kraurosis.
• Atrophic cystitis is also successfully treated with the use of this drug.
• Therapy of vaginal ulcers.

Most often Oviplo Clio (candles), reviews about which we will consider, give a positive result after the first application, but the therapy must be passed completely to fix it for a long time.

Who does not show therapy?

Despite the good effect of therapy with the use of Ovip Cleo suppositories, the instructions for use contain a number of contraindications to treatment:

• Oncology of the breast.
• Malignant neoplasms are estrogen dependent.
• Genital bleeding.
• Hyperplasia of the endometrium, which can not be treated with drugs.
• There is either a history of thrombosis and thromboembolism.
• Do not prescribe the drug for conditions preceding thrombosis: ischemic attacks, angina.
• The presence of risk factors for the development of thrombosis, include: heart valves, atrial fibrillation, cerebral arteries or coronary artery disease, uncontrolled hypertension, smoking.
• Thrombophlebitis.
• Cholestatic jaundice.
• The presence of such a diagnosis as otosclerosis.
• Diseases of the liver in an acute form or in an anamnesis. The drug is not prescribed until all the indicators come back to normal.
• Presence of hereditary factors predisposing to the development of thrombosis.
• Period of bearing the baby.
• Breast-feeding.
• Excessive sensitivity to the components of the drug.

The list is quite extensive, so before the therapy consultation with a doctor is mandatory.

You can also name the list of diseases in which treatment with the drug is allowed, but it is necessary to strictly dose and comply with the scheme of use:

• Diabetes.
• Liver adenoma.
• Frequent migraines.
• Epilepsy.
• Inflammatory processes in the pancreas.
• Bronchial asthma.
• Cardiac ischemia.
• Edema.
• Heart failure.

Scheme of therapy and dosage

Candles "Ovipol Clio" (instructions for use contains this information) are used only intravaginally and most often at bedtime. Depending on the severity of the pathology and condition of the body, the dosage and duration of therapy differ:

1. If there is atrophy of the mucous membrane of the urogenital tract, the doctor appoints 1 candle every day for several weeks, and then the dosage is reduced, depending on the symptoms present up to 1 suppository 2 times a week.
2. If pre- or post-operative therapy is used, it is recommended to use 1 suppository daily for 14 days.
3. If it is necessary to clarify the diagnosis, the drug is prescribed at 0.5 mg every other day for 7 days.
4. To treat senile colpitis, one candle is prescribed per night for two weeks.

If the patient misses the drug, then it is necessary to renew it at the first opportunity, but only do not use 2 suppositories in one day, double dosing is unacceptable. It must be remembered that attempts to use the drug orally can result in severe bleeding, headache, vomiting.

Undesirable manifestations during drug therapy

"Ovipol Cleo" - candles (reviews confirm this), which are most often tolerated by the body well, as a rule, the manifestation of side effects is associated with exceeding the recommended dosage. Patients can sense:

• Headache.
• Soreness in the muscles.
• Dizziness.
• Violation of the stomach.
• Feeling of bursting in the mammary glands.
• Itching of the genitals.
• Edema.
• In rare cases, visual impairment was observed.
• Violation of coordination of movements.
• Convulsions.

This drug is considered quite safe, if you follow the dosage and use it correctly.

Interaction of Ovipole Clio with other drugs

Always when choosing a therapy the doctor must find out from the patient what medications he is taking at the moment. This must always be taken into account, since drugs can influence the effects of each other. Ovip Clio candles strengthen the effect of the following medicines:

• Preparations of the barbiturate group.
• Medicines for the therapy of epilepsy.
• Antibacterial drugs.
• Analgesics.
• Anticonvulsants.
• Hypoglycemic drugs.
• Hormones of the thyroid gland.
• Diuretics.
• Anticoagulants.
• Male sex hormones.

When prescribing the drug in conjunction with other drugs, you need to adjust the dosage.

Special instructions for drug treatment

If long-term therapy with Ovipol Cleo is to be performed, periodic examinations are recommended. Before the beginning of admission and every six months to undergo an examination with a gynecologist and mammologist. Use candles during menopause in women can be if the symptomatology reduces the quality of life of the patient.

Always before appointment, the doctor must correlate the benefits and harms of therapy. During treatment, a woman should regularly report all cases of vaginal bleeding, the appearance of jaundice, engorgement of the mammary glands. If there are pain in the legs, in the chest, shortness of breath, then the doctor will appoint a thorough examination.

Treatment will have to be canceled if:

• Diagnosis of a malfunction of the liver.
• A sharp increase in blood pressure.
• Develops a migraine.
• Phlebitis.

If long-term estrogen treatment is performed, the risk of developing endometrial cancer is increased. The higher the dosage and the duration of therapy. The duration of hormone replacement therapy affects the risk of developing breast oncology. Against the background of treatment, the density of the breast increases, which complicates the study.

If treatment lasts more than 5 years, the risk of developing ovarian cancer also increases. A small part of patients develops, as an adverse event, a malignant tumor of the liver. It significantly increases the risk of intra-abdominal bleeding.

HRT increases the risk of developing thromboembolism by almost 3 times. Especially it is great in the first year of treatment. At the time of prescribing, all risk factors must be considered, and if therapy is performed before surgery, then VTE prevention is important. The drug should be canceled for a while, and after the operation it can be resumed only after the patient has recovered.

In the elderly, the risk of stroke increases. If treatment is assigned to a young patient whose relatives have thrombosis, then a study is conducted for the presence of thrombophilic disorders. If any are found, then hormone therapy is contraindicated.

With a tendency to edema, the presence of kidney pathologies, especially with kidney failure, hormone therapy should be administered only under the supervision of a doctor.

Given that the main active ingredient in candles (estriol) increases the lithogenicity of bile, that is, the risk of developing cholelithiasis.

Consequences of prolonged therapy with estriol

If long-term treatment with sex hormones is to be performed, the vaginal microflora normalizes, the symptomatology of the elderly colpitis decreases, but it must be borne in mind that there is a risk of pathological processes.

1. Often the side effect of prolonged therapy is endometrial cancer. The risk depends on the dosage and duration of treatment.
2. The appearance of malignant neoplasms in the mammary gland.
3. Cancer of the ovaries.
4. Neoplasms in the liver.
5. In elderly patients the risk of ischemic stroke is great.
6. Cholelithiasis.
7. The onset of dementia.

During prolonged treatment, it is necessary to periodically visit a specialist to monitor the course of therapy and its effectiveness, and to monitor the slightest deterioration in the patient's condition.

Oviplo Clio (candles): analogues

Each drug has its own analogues, as a rule, they have the same active substance, but the choice should be carried out under the guidance of a doctor. If we consider Ovipol Clio (candles), their price ranges from 500 to 600 rubles per package. For the drug in pharmacies you can find Russian analogues, for example:

• Ornion.
• "Estrovagin."

But there are preparations of imported production:

• "Ovestin".
• "Elvagin".
• «Estrokad».

It is necessary to remember, if you decide to replace the import analogue "Ovipol Clio" (candles), the price can be much higher, and the result is almost the same. So is it worth overpaying for a foreign manufacturer? It is always necessary to discuss all issues related to the replacement of the drug. The active substance may be the same, but the presence of ancillary components, which may also have an effect on the tolerability of the agent, can not be discounted.

Patient Reviews

If you review the reviews of patients who have been taking therapy with this drug, then you can find different opinions. Some respond positively, note that a few days after the start of use, the vaginal dryness has gone, the itching has disappeared, and the symptoms of the climacteric period have become less pronounced. Women note that "Ovipol Cleo" copes no worse than the "Ovestin".

But some women did not help the candles or caused unpleasant sensations, burning. If such symptoms appear during treatment, then it is necessary to tell the doctor, and then the drug will have to be replaced or adjusted dosage. We can say that the body has its own characteristics, individual pathology, so there is no universal means that would help all equally.

Any hormonal disorders can now be effectively treated if you contact the doctor in a timely manner. Selection of drugs should be done only by a doctor. Self-medication in such situations is fraught with serious complications.