"Ovenkor": instructions for use. Lipid-lowering drugs

Unfortunately, an elevated cholesterol level is a problem that many people face, especially in old age. The accumulation of this substance in the body leads to severe consequences, including the disruption of the normal operation of the cardiovascular system. In such cases, patients simply need lipid-lowering drugs.

Of course, the modern pharmaceutical market offers a huge selection of such medicines. Quite often doctors recommend patients receiving the drug "Ovenkor". Instructions for use here are simple enough, adverse reactions occur rarely, but the visible effect appears a few weeks after the start of therapy. So what is this tool? What properties does it have? Are there any contraindications? Answers to these questions will be of interest to many readers.

Composition and form of release

The drug "Ovenkor" is a medicine that is available in the form of round tablets with a hard film membrane. The main active substance here is simvastatin. By the way, in the pharmacy you can buy a drug with a dosage of 10 or 20 mg of the active ingredient in each tablet.

Naturally, some auxiliary substances are present in the formulation. In particular, lactose, butyl hydroxy anisole, as well as citric acid, microcrystalline cellulose, castor oil, magnesium stearate, ascorbic acid, corn starch, talc, titanium dioxide, polyethylene glycol 4000, hydroxypropylmethylcellulose and pregelatinized starch are used in the production.

Pharmacological properties

"Ovenkor" is a medicine that has several useful properties. Penetrating into the body, the active substance of the drug enters into metabolic reactions, during which the activity of the specific enzyme HMG-CoA reductase is inhibited. It is this substance that catalyzes the initial stages of cholesterol synthesis.

Thus, this drug reduces the level of triglycerides and low density lipoproteins in blood plasma, which, accordingly, reduces the total cholesterol. Along with this, the drug increases the content of high-density lipoproteins, which also positively affects the work of the body.

It is worth noting that really visible changes appear two weeks after the start of the drug. To achieve maximum therapeutic effect, a course of treatment of 4-6 weeks is needed. As a rule, the effect of the drug stops after the abolition of tablets - if the diet is not followed and other recommendations of the doctor, the level of cholesterol gradually begins to return to the initial indicators.

The drug is very quickly adsorbed by the walls of the digestive tract. The maximum concentration of active substances in the blood is observed after 1-2.5 hours after taking the pill. The degree of binding to plasma proteins is 95%. Metabolism of the drug occurs in the liver tissues. The bulk of metabolites are eliminated from the body along with the calves. Approximately 10-15% goes with urine.

Main indications for use

In which cases is it expedient to take the drug "Ovenkor"? Indications for use are any disorders that are associated with the accumulation and increase in the level of cholesterol in the body. Quite often, doctors prescribe this medicine to patients with primary hypercholesterolemia, especially when the right diet, weight loss, exercise and other activities do not have the expected effect. The course of therapy prevents the further development of coronary atherosclerosis.

Lipid-lowering drugs are also effective in combined forms of hypertriglyceridemia and hypercholesterolemia, which are not corrected by non-pharmacological methods.

In some cases, the drug is prescribed for patients suffering from coronary heart disease. In particular, it is used to prevent myocardial infarction. The drug slows the development of atherosclerosis of the coronary vessels, reduces the likelihood of risk in revascularization procedures, and also reduces the likelihood of developing cardiovascular disorders such as transient ischemic attacks and stroke.

"Ovenkor" preparation: instructions for use

Before starting therapy, the patient must undergo a full medical examination. Only a doctor can correctly formulate a regimen of treatment with the drug "Ovenkor". The instructions for use contain only general recommendations.

As a rule, patients are recommended to take the drug once a day, preferably in the evening (for example, before going to bed). The rate of adsorption does not depend on the intake of food, but the tablet needs to be washed down with plenty of water. The daily dose directly depends on the patient's condition and ranges from 10 to 80 mg of simvastatin. Dose change (decrease or increase) should be done at intervals of four weeks. According to statistics, the maximum therapeutic effect in most cases is achieved with the intake of 20 mg of drug per day. Throughout the treatment, the patient must adhere to a diet low in cholesterol.

Are there any contraindications to admission?

Many patients are interested in questions about whether all the categories of patients can take the drug "Ovenkor". Instruction for use says that the medicine has a number of contraindications, which must be read. In the first place, it is worth mentioning the increased sensitivity to simvastin, drugs of the statin series, as well as the auxiliary substances that are present in the tablets.

This drug is not prescribed for patients suffering from porphyria, certain diseases of skeletal muscles (for example, myopathy), as well as acute violations in the liver that are associated with increased activity of enzymes. The drug is also not used to treat children and adolescents, pregnant women (there is evidence of adverse effects on the fetus).

Relative contraindications include arterial hypotension, acute infections, endocrine disorders, metabolic disorders, and alcoholism. Also, the drug is not prescribed for patients who have recently undergone severe trauma, surgery or organ transplantation.

Possible side effects and complications

In some cases, therapy may be associated with some complications. In particular, sometimes patients complain of digestive system disorders, which are accompanied by severe nausea, vomiting, stool disorders, abdominal pain. Much more rarely observed an increase in activity of liver enzymes, the development of hepatitis, inflammation of the pancreas.

The drug may negatively affect the nervous system. In particular, treatment can be accompanied by such violations as persistent headaches, blurred vision, dysfunctional sensations, as well as dizziness and insomnia. Much less often observed development of asthenic syndrome, peripheral neuropathy, as well as the emergence of parasthesias and muscle cramps.

There may be side effects from the musculoskeletal system. Some patients develop myopathies and myalgias, less often rhabdomyolysis. Also, allergic reactions are possible, which are accompanied by skin rash, itching, urticaria, swelling, shortness of breath, hot flashes, skin flushing. Less often there is an increase in sensitivity to light, the development of vasculitis, arthritis, angioedema. Other side effects include decreased potency, anemia, increased heart rate, acute renal failure.

Overdose, its symptoms and methods of treatment

In fact, cases of overdose are recorded very rarely and, as a rule, are accompanied by exacerbation of side effects. If the drug was taken recently, it is advisable to induce vomiting, rinse the stomach and take the sorbent. Treatment in this case is symptomatic. It is extremely important in the first few days to monitor the work of the kidneys and liver. In the case of the development of renal failure (it is extremely rare) and other serious complications, hemodialysis is indicated.

Interaction with other drugs

Before starting treatment, be sure to notify your doctor about the medicines you are taking at the moment. The combination of antifungal agents (eg, ketoconazole) with this drug increases the risk of myopathy. In the same way, "Ovencor" interacts with cytostatics, immunosuppressants, fibrates and some antibiotics. Contraindicated simultaneous reception of "Ovenkor" with high doses of nicotinic acid. By the way, for the duration of therapy, doctors strongly recommend that you stop using grapefruit juice.

Are there any effective counterparts?

Unfortunately, for some reason, not all patients are suitable for this medicine. Therefore, many are interested in whether it is possible to replace the drug "Ovenkor" with something? Analogues, of course, exist.

For example, tools such as Vazilip, Zovatin, Zokor, and Simvastatin are considered quite effective substitutes. The same pharmacological properties are possessed by "Simgal", "Simvor" and "Holvasim".

In any case, it is worthwhile to understand that you can not arbitrarily stop taking the drug "Ovenkor". Analogues can be selected only by the treating specialist. Self-medication can lead to unpleasant and even dangerous consequences.

Analogue of the preparation "Simvastatin": instructions for use, price

This drug is a direct analog of the "Ovencor", since it contains the same active component. That is why many patients are interested in additional information about the medicine "Simvastatin". The instruction on application, the price, properties - all this, very important moments.

The drug is also available in the form of tablets and has almost the same composition. It has the same hypolipidemic properties, lowers cholesterol in the blood. The principle of application is the same - the daily dose is prescribed for a single dose, and depending on the state of health of the patient, it can be from 5 to 80 mg of simvastatin.

But the price of the drug is much less. For example, 30 tablets with a dosage of 10 mg will cost you 100 rubles, and "Simvastatin" in 20 mg is about 150-200 rubles (for the same number of tablets). Because of the low cost, many patients choose this particular drug.

How much is the medicine?

Many people are interested in additional information about the drug "Ovenkor". Price, analogues, patient feedback are extremely important issues. Moreover, for many patients, the cost of a given drug is of prime importance.

So how much will the "Ovenkor" cost. The price, of course, depends on many factors. For example, in consideration it is necessary to take firm-manufacturer, a dosage and quantity of tablets, and also a price policy of a drugstore, etc. Approximately 450-550 rubles you can buy a package of 30 tablets "Ovenkor" (20 mg). The price for the same number of tablets, but with a dose of 10 mg is slightly less - 350-400 rubles.

Reviews of patients and doctors about the medicine

Many people are looking for additional information about this medicine. What really is the "Ovencor"? The doctors' comments about the drug are mostly positive. Specialists do note that this drug is well tolerated by patients. Moreover, it helps to reduce cholesterol as quickly as possible and prevent the development of dangerous consequences.

What do the patients themselves say about the "Ovenkor" preparation? The patients' testimonies confirm that the medicine helps to cope with a lot of problems, especially if you combine it with non-medicamentous methods of treatment. Some patients develop side effects that occur with a decrease in the daily dose. Perhaps the only drawback is the cost of the drug, since there are cheaper and more affordable analogs.